1. Wk 6 Chronic Inflammation Flashcards Preview

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Flashcards in 1. Wk 6 Chronic Inflammation Deck (31):
1

origins of Chronic inflam

1. follows acute inflam
2. repeated attachs of acute inflam
3. begins insidiously

2

What (3) sub will be present at an immune response ***

1. macrophage
2. lymcytes
3. plasma cells
- the 3 cells that will identify chronic inflam

3

What (3) sub activate macrophages to do phagocytosis

1. Y interferon
2. immunoglobulin
3. complement

4

What (3) damaged tissues will be repaired

1. new blood vessels- cap.
2. fibroblasts
3. fibrosis

5

What are three characteristics of Chronic inflam (5)

1. insidious onset
2. progressive
3. vasodilation: mild- no redness/hotness
4. scanty exudate: no edema
5. B & T lymphocytes, plasma cells & macrophages

6

Does chronic inflam have exudate or transudate?

exudate

7

Name (4) cinflam cells:

B & T lymphocytes
plasma cells
macrophages

8

monocytes are ___

macrophages

9

Monocyte phagocytosis is activated by (2)

immune: y interferon
non immun: bact endotoxin

10

Monocytes are:
1. ___ size of cells
2. active ___
3. ____ enxymes

1. large in size
2. acitve metabolism
3. lysosomal enzymes

11

Name (4) bact. killing oxygen kill radicals

O2
H2O2
HOCl
O3

- O2 independant = enzymes

12

What are oxygen independant mech for killing bacteria

enzymes

13

___cytes product fibroblast growth factor & T/B lymphocytes growth promoting factor

monocytes

14

___: produce Antibodies agaisnt foreign antigens or modified tis antigen

plasma cells

15

____: mobilized in both antibody and cell mediated immune rxn

lymphocytes

16

___: immune rxn mediated by IgE & parasitic infections

eosinophils

17

5 types of chronic inflam cells

1. monocytes
2. plasma cells
3. lymphocytes
4. eosinophils
5. neutraphils

18

What are the two different types of granulomatous cells (2)

eitheloid cells - mod macrphages
giant cells

19

20+ epitheloid cells will fuse together to make _____ cells

giant

20

Name two types of giant cells

1. langhan's giant cells
2. foreign body giant cells

21

____ cells have a center of necrosis

granuloma

22

4 types of cells located in the granuloma

1.peripheral rim of lymphocytes
2. plasma cells
3. neutrophils
4. collagen fibers

23

(3) infections that are granulosum

1. TB
2. leprosy
3. syphilis

24

Name 1 type of dx that is granulosum

silicon dust --> ex of foreign body gradnulosum

25

Fever is caused by liberation of pyrogens: ___ & ____

IL-1 & TNF

26

_____ is the heat regulating center in the brain

hypothalmus

27

to cause a fever, the hypothalmus sends SP stim to the skin do to vaso____

vasoconstriction
- this will decrease heat loss = fever

28

Leukocytes are released from ____

bone marrow
(TNF & IL-1)

29

prolong infection stim bone marrow ____ cells

stem cells

30

Name 4 rxns that will occur during a fever

sleepiness
decr. BP
incr. fibrinogen
incr. Erythrocyte sedimentation rate (ESR)

31

If the lymph nodes failure to localize the inflam the infection will go to the blood ____ cells

reticuloendothelial cells