Flashcards in 1. Wk 6 Chronic Inflammation Deck (31):
1
origins of Chronic inflam
1. follows acute inflam
2. repeated attachs of acute inflam
3. begins insidiously
2
What (3) sub will be present at an immune response ***
1. macrophage
2. lymcytes
3. plasma cells
- the 3 cells that will identify chronic inflam
3
What (3) sub activate macrophages to do phagocytosis
1. Y interferon
2. immunoglobulin
3. complement
4
What (3) damaged tissues will be repaired
1. new blood vessels- cap.
2. fibroblasts
3. fibrosis
5
What are three characteristics of Chronic inflam (5)
1. insidious onset
2. progressive
3. vasodilation: mild- no redness/hotness
4. scanty exudate: no edema
5. B & T lymphocytes, plasma cells & macrophages
6
Does chronic inflam have exudate or transudate?
exudate
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Name (4) cinflam cells:
B & T lymphocytes
plasma cells
macrophages
8
monocytes are ___
macrophages
9
Monocyte phagocytosis is activated by (2)
immune: y interferon
non immun: bact endotoxin
10
Monocytes are:
1. ___ size of cells
2. active ___
3. ____ enxymes
1. large in size
2. acitve metabolism
3. lysosomal enzymes
11
Name (4) bact. killing oxygen kill radicals
O2
H2O2
HOCl
O3
- O2 independant = enzymes
12
What are oxygen independant mech for killing bacteria
enzymes
13
___cytes product fibroblast growth factor & T/B lymphocytes growth promoting factor
monocytes
14
___: produce Antibodies agaisnt foreign antigens or modified tis antigen
plasma cells
15
____: mobilized in both antibody and cell mediated immune rxn
lymphocytes
16
___: immune rxn mediated by IgE & parasitic infections
eosinophils
17
5 types of chronic inflam cells
1. monocytes
2. plasma cells
3. lymphocytes
4. eosinophils
5. neutraphils
18
What are the two different types of granulomatous cells (2)
eitheloid cells - mod macrphages
giant cells
19
20+ epitheloid cells will fuse together to make _____ cells
giant
20
Name two types of giant cells
1. langhan's giant cells
2. foreign body giant cells
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____ cells have a center of necrosis
granuloma
22
4 types of cells located in the granuloma
1.peripheral rim of lymphocytes
2. plasma cells
3. neutrophils
4. collagen fibers
23
(3) infections that are granulosum
1. TB
2. leprosy
3. syphilis
24
Name 1 type of dx that is granulosum
silicon dust --> ex of foreign body gradnulosum
25
Fever is caused by liberation of pyrogens: ___ & ____
IL-1 & TNF
26
_____ is the heat regulating center in the brain
hypothalmus
27
to cause a fever, the hypothalmus sends SP stim to the skin do to vaso____
vasoconstriction
- this will decrease heat loss = fever
28
Leukocytes are released from ____
bone marrow
(TNF & IL-1)
29
prolong infection stim bone marrow ____ cells
stem cells
30
Name 4 rxns that will occur during a fever
sleepiness
decr. BP
incr. fibrinogen
incr. Erythrocyte sedimentation rate (ESR)
31