Infections of the Skin II (4) Flashcards

1
Q

What are characteristics of staphylococcus?

A

facultative anaerobic
gram-positive cocci

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2
Q

Which staphylococci are coagulase positive?

A

s. aureus
s. pseudintermedius
s. hyicus

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3
Q

Which staphylococci are coagulase negative?

A

s. epidermis

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4
Q

Which staphylococci are resident?

A

s. epidermis

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5
Q

How does staphylococcus infect the dermis once the epidermis is damaged?

A

binding to the host’s extracellular matrix (through ECM-binding proteins)

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6
Q

What virulence factors/mechanisms do staphylococcus sp. have that help in survival, multiplication, and spread?

A

resist phagocytosis - capsule and clot formation

survive within phagocytotic cells

proteases digest host tissue and damage skin

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7
Q

How do proteases help in staphylococcus spread?

A

digest host tissue and damage skin

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8
Q

What are the exotoxins for staphylococcus?

A

leukocidin
hemolysin
coagulase

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9
Q

In staphylococcus, you usually see mixed bacterial infections, as they are the primary invaders, and the production of _____ allows ______

A

exotoxins

allows secondary invasion by other bacteria

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10
Q

How do you treat staphylococcus?

A

address the underlying/predisposing issues

antibiotics

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11
Q

What is another word for greasy pig disease?

A

exudative epidermitis

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12
Q

What is greasy pig disease caused by? It is generally [contagious/non-contagious]

A

staphylococcus hyicus

contagious - HIGHLY

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13
Q

What is greasy pig disease characterized by?

A

excessive sebaceous secretion, exfoliation, and exudation on the skin surface

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14
Q

T/F: Pigs that have exudative epidermitis are highly pruritic

A

FALSE - are non-pruritic and have a greasy exudate

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15
Q

How does s. hyicus enter the skin?

A

bite wounds - appears unable to penetrate intact skin

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16
Q

In greasy pig disease, virulence is linked to the production of _______

A

exfoliative toxins

17
Q

In greasy pig disease, what do exfoliative toxins do?

A

reduce cell-cell adhesion of keratinocytes in the superficial epidermis

18
Q

How do you manage exudative dermatitis?

A

be mindful of abrasive surfaces and disinfect them

disinfect skin of udder before farrowing

19
Q

What is the etiologic agent for dermatophilosis?

A

dermatophilus congolensis

20
Q

What kind of parasite is dermatophilus congolensis?

A

obligate parasite

21
Q

What is dermatophilosis characterized by?

A

exudative epidermitis

with scab formation (matted hair, crust/scabn formation, and wart-like lesions)

22
Q

Dermatophilosis is most common in _____ and ______

A

ruminants

horses

23
Q

Strawberry foot rot is an example of _____

A

dermatophilosis

24
Q

Dermatophilosus congolensis is a gram-[positive/negative] [facultative/obligate] [aerobe/anaerobe]

A

gram-positive

facultative anaerobe

25
Q

What is the characteristic morphology of dermatophilus congolensis?

A

rail-road tracks

26
Q

Who are the reservoirs for dermatophilus congolensis?

A

carrier animals

27
Q

How is dermatophilus congolensis transmitted?

A

by direct contact

via mechanical vectors

infected fomites

28
Q

A _____ lesion in dermatophilus congolensis is formed by clotting of serous exudate

A

paintbrush

29
Q

T/F: Dermatophilus congolensis have a period of growth without division and form elongated bacteria called hyphae

A

TRUE

30
Q

Dermatophilus congolensis causes _____

A

an exudative epidermitis

31
Q

What does dermatophilus congolensis result in?

A

separation and characteristic scab formation

organisms remain primarily in the scab

32
Q

T/F: Dermatophilosis is non-pruritic

A

TRUE

are painful though

33
Q

How do you treat dermatophilosis?

A

eliminate predisposing factors

topical treatment (less effective)

antibiotics