Respiratory Infections I (25) Flashcards
Dr. Erol
What is mammalian tuberculosis? Who does it affect?
a re-emerging, granulomatous diease in animals and people
practically ALL species of vertebrates
____ TB is still significant zoonosis in non-industrialized countries of the world
Bovine
What is the causative agent for tuberculosis in cattle? It is a [mild/severe] disease
mycobacterium bovis
severe
What is the distribution of bovine TB?
once a world-wide problem, but lots of TB-free countries now
eradication programs still in progress
What is the status of bovine TB in the US?
How is m. bovis transmitted?
humans: ingestion of unpasteurized dairy products or undercooked meat
aerosols
cattle (reservoir host)
- aerosol
- ingestion
- cutaneous, genital, congenital
M. bovis is very rare in countries with _____ and ______
pasteurized milk
bovine tuberculosis eradication programs
How does tuberculosis (Mtb or Mb) affect people?
cervical lymphadenopathy (scrofula) - lupus vulgaris
localized skin isease “butcher’s wart”
pulmonary disease
genitourinary disease
What are signs of tuberculosis in animals - general?
progressive emaciation, lethargy, weakness, anorexia, and a low-grade fluctuating fever
What are signs of tuberculosis in animals - respiratory?
bronchopneumonia causes a chronic, intermittent, moist cough with later signs of dyspnea and tachypnea
destructive lesions of the granulomatous bronchopneumonia may be detected on auscultation and percussion
What are clinical signs of tuberculosis in cattle? What can be involved?
evident only in advanced cases, can still appear to be in good health
loss of condition
mammary tissue - marked induration of affected quarters and enlargement of supramammatory lymph nodes result
A cow has marked induration of affected quarters, swollen lymph nodes, and loss of condition. This is a microscopic appearance of a tubercle. How did the cow most likely acquire this disease? What is the causative agent and illness?
aerosols
mycobacterium bovis - bovine tuberculosis
A cow necropsy revealed post-mortem lesions in the uterus and lung. What could this be?
bovine tuberculosis
How do you diagnose bovine tuberculosis?
tuberculin skin test, based on delayed-type hypersensitivity
Where do you test for tuberculosis for preliminary screening of cattle? Re-testing?
caudal fold
single cervical - cervids
comparative cervical - re-test
How do you diagnose bovine tuberculosis?
histopathology/microscopic exam
How do you control bovine tuberculosis?
treatment inappropriate
controlled by test and slaughter or test and segregation methods
disinfect
rodent control
What is the causative agent of avian tuberculosis?
m. avium complex, serotypes 1-3
Diagnosis of avian tuberculosis is based on _____
post-mortem findings and demonstration of ZN_positive bacilli in smears from lesions
Who else can get infected with m. avium?
immunocompromised humans and rarely in cats, dogs, and horses
pigs
What are clinical findings of feline leprosy?
subcutaneous nodules, which are fleshy and freely movable and tend to ulcerate
usually confined to head region or limbs
What is m. fortutum?
rapidly growing organism associated with mastitis in cows, pulmonary infections in dogs, lymph node lesions in pigs, and cutaneous lesions in cats and dogs
