2 Intro to infectious Dis [3] Flashcards Preview

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Flashcards in 2 Intro to infectious Dis [3] Deck (10)
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1
Q

2 leading causes of death from infectious diseases world wide

A

Pneumonia (8-10%, 10 mil/year)

Diarrhea (2 mil/year)

2
Q

Age group preferentially affected by infectious disease syndromes

A

diarrheal disease is in the young and old

3
Q

Identify the leading cause of morbidity and death with diarrhea

A

dehydration

- rehydration is mainstay of therapy

4
Q

Species that cause Noninflammatory diarrhea

A
Norwalk virus
rotavirus
giardia lamblia
cholera
ETEC
5
Q

Species that cause inflammatory diarrhea

A
c. jejuni
shigella
salmonella
Ecoli 0157:H7
C. difficile
E. histolytica
6
Q

Inflammatory vs noninflammatory diarrhea

A

Inflammatory:
- increase temp, WBC, RBC, involves the COLON

NON-inflammatory: (watery)
- involes the SMALL BOWEL

7
Q

Structure of cholera toxin

A

A:5B

A - active: secretes toxin into epi cells
B - binding: binds to epi cells

8
Q

Signs of dehydration

A
decrease pulse 
low BP
poor skin turgor
sunken eyes
decreased urine
met acidosis
hypoglycemia
hypokalemia
9
Q

Travelers diarrhea

A

Enterotoxigenic E. coli (ETEC)

10
Q

Norovirus/Norwalk virus

A

family/community epidemics (winter) - like rota

transmitted thru: f-o, contamination, shellfish, and water

Older children and adults
(comes fast, goes away fast)