Small group Liver II + cancer Flashcards Preview

DEMS Unit 1 > Small group Liver II + cancer > Flashcards

Flashcards in Small group Liver II + cancer Deck (10):
1

SBP can present underwhelmingly (asymptomatic) but can present with hepatorenal syndrome bc they got sicker, what test can you get done?

Diagnostic paracentesis

2

If you have Type 1 Hepatorenal syndrome (HRS) what is the tx?

liver transplant - curative

3

Posthepatic portal HTN can be due to

Hepatic Vein Thrombosis

RHF
Constrictive pericarditis

4

HBV vs HCV, which one has an 85% chance of going on to chronic hepatitis?

HCV

5

The GRADE of chronic liver disease is related to ________.

The STAGE of chronic liver disease is related to _________.

inflammation and necrosis

fibrosis

6

Drug you give to tx hepatic encephalopathy

lactulose
- non-absorbable sugar used as laxative by pulline/retaining water in the colon --> diarrhea to flush NH3 from the colon (less absorbed)

Rifaximin - non absorbable antibiotic - red bacteria that cause NH3

7

Other than HH, what other diseases elevate ferritin?

Infections

INflammatory

- so check CRP and ESR
- if nl then not one of these, prob HH

8

Most commonly affected gene in HH?

HFE
TfR2

HFE
- nothern euro
- Mut C282Y
Homozygosity = disease
Heterozygosity = no diease

9

When would Iron be found in the hepatocyte vs inside macrophages.

Hemochromatosis: inside hepatocytes - storage unit

Hemosiderosis: Inside macrophages (Kupffer) - damage

10

joint symptoms is seen in 44% of ____

hemochromatosis