Review Flashcards
(28 cards)
acetaminophen is a hepatotoxin that causes ______ necrosis WITHOUT a significant inflammatory cell infiltrate
centrilobular coagulative necrosis
Acute infxn has Ig_ infxn. Sustained infxn is Ig_
M acute
G for sustained immunity
There is a vaccine for which hepatitis?
A + B
elevated Ig_ is associated with autoimmune hepatitis
IgG
ELEVATED Ig_ IS associated with primary biliary cirrhosis
IgM
PAS-positive, diastase resistant globules in hepatocytes
PASD stain
alpha-1-antitrypsin deficiency
–> emphysema + cirrhosis
PSC dx is ___ in nature
radiologic for strictures
anti smooth muscle antibodies
- IgG
- ana
autoimmune hepatitis
AMA + IgM
Two M’s
PBC
Plasma cell rich interface and centrilobular hepatitis
Autoimmune
plasma cells = autoimmune
PBC population
middle age women
PSC population
Male predominance
Autoimmune hepatitis population
female
Also PBC
Granulomatous lymphocytic cholangitis/florid duct lesion
PBC
Pruritis (itchyness) and jaundice in middle aged women
Primary biliary cirrhosis
misnomer, doesnt have to have cirrhosis
Most common benign tumor found in liver
hemangioma
(most common of all)
(most common malignant is hepatocellular carcinoma)
Tumor of bile ducts
cholangiocarcinoma
Tumor of hepatocytes
hepatocellular carcinoma
hepatocellular adenoma
Focal nodular hyperplasia
Proliferation/hyperplasia/ nonneoplastic
focal nodular hyperplasia
Hepatocellular adenoma pop
women
which liver cancer is associated with oral contraceptives
hepatocellular adenoma
which liver cancer is associated with cirrhosis
hepatocellular carcinoma
which liver cancer is associated with gland formation with marked desmoplasia
cholangiocarcinoma
bile duct
which liver cancer is associated with PSC
cholangiocarcinoma
“cholang”
(primary sclerosing cholangitis)
