Flashcards in Small GRoup Lower GI Deck (11):
TTG serology tests for?
- non bloody diarrhea
- abdominal bloating w/ discomfort
Intraepithelial inflammation and lost of villus and expansion of lamina propria:
Celiacs disease (autoimmune etiology)
Celiac = autoimmune
wheat = allergic inflamm sys dysfxn
Gluten sens = non autoimmune non allergic
Why do you have to run a quantitative IgA test when testing for TTG for celiacs?
Rule out IgA deficiency (present in 2-3% of pts with celiacs - challenge)
- if pt is not IgA deficient, other test results should be valid
IgA against TTG or DGP
loss of haustral folds + lead pipe colon, shortened colon
Chronic UC (IBD)
Continuous ulceration of mucosal surface extending from distal ascending colon to rectum
- pseudopolyps may be present
- wall fibrosis
- fat wrapping
- granuloma formation in 35%
colonic involvement beginning in rectum
- L sided involvement
Crypt absesses are seen in?
Crohns and UC
Malignant potential is seen in crohns or UC?