2bio5 Flashcards
oxidative phosphorylation
-parts
-location
-redox
-gradient
-proteins
-atp synthase
-carriers
-oxygen
Oxidative phosphorylation is the last pathway. It has two parts, the ETC and chemiosmosis. It occurs on and on the inner membrane of the mitochondria. Each time electrons are passed it’s a redox reaction, and it happens because each successive enzyme or coenzyme has a greater electronegativity. As electrons are passed down their energy is used to translate H+ from the matrix into the intermembrane space. The resulting chemical gradient then holds the potential energy of glucose. The membrane proteins are NADH dehydrogenase, the cytochrome b-c complex, cytochrome oxidase and atp synthase. Atp synthase is a multi enzyme complex that allows H+ to travel along the electrochemical gradient, and uses the kinetic energy to make atp. 32 atp are made. Each NADH contributes enough to the gradient to cause atp synthase to make three atp. FADH2 drops its electrons after the first protein channel so it contributes enough to make 2 atp. Ubiquinone is a Mobile election carrier that moves from complexes one and two to three. cytochrome C is a mobile electron carrier that move between complexes three and four. The pathway needs oxygen since it is the final electron acceptor. Oxygen therefore drives the ETC. It also picks up H+ to become water. Each O2 molecule can make 2 waters.
