4) Adrenergic Receptor Agonists - Antagonists Flashcards Preview

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Flashcards in 4) Adrenergic Receptor Agonists - Antagonists Deck (126)
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1

What is the class for Norepinephrine (Levophed)

Non-selective agonist

2

What is the mechanism for Norepinephrine (Levophed)

Agonist: alpha 1, alpha 2, beta 1

3

What are the therapeutics for Norepinephrine (Levophed)

Acute Hypotension

4

What are the important side effects for Norepinephrine (Levophed)

Hypertension; arrythmias; headache

5

What is the class for Epinephrine

Non-selective agonist

6

What is the mechanism for Epinephrine

Agonist: alpha 1, (alpha 2), beta 1, beta 2

7

What are the therapeutics for Epinephrine

Anaphylactic shock; combined with local anesthetics; glaucoma

8

What are the important side effects for Epinephrine

Palpitation; arrhythmias; headache

9

What is the class for Amphetamine

Indirect acting

10

What is the mechanism for Amphetamine

Increases release of NE

11

What are the therapeutics for Amphetamine

ADHD, narcolepsy, recreation

12

What are the important side effects for Amphetamine

Hypertension, insomnia, anxiety, arrhythmias

13

What is the class for Isoproterenol (Isuprel)

Non-selective beta agonist

14

What is the mechanism for Isoproterenol (Isuprel)

Agonist: beta 1, beta 2

15

What are the therapeutics for Isoproterenol (Isuprel)

shock; heart block

16

What are the important side effects for Isoproterenol (Isuprel)

Palpitation; tachyarrhythmia; headache

17

What is the class for Dobutamine

beta 1-selective beta agonist

18

What is the mechanism for Dobutamine

Agonist: beta 1

19

What are the therapeutics for Dobutamine

Cardiac decompensation; shock; heart block

20

What are the important side effects for Dobutamine

Tachyarrythmias; hypertension

21

What is the class for Albuterol (Proventil)

beta 2-selective beta agonist

22

What is the mechanism for Albuterol (Proventil)

Agonist: beta 2

23

What are the therapeutics for Albuterol (Proventil)

Prevent or reverse exercise-induced bronchospasm; mild asthma; COPD

24

What are the important side effects for Albuterol (Proventil)

Can mask progressively severe inflammation

25

What are the other side effects for Albuterol (Proventil)

Tachycardia, muscle tremor

26

What are the miscellaneous for Albuterol (Proventil)

10-15 minutes to take action, 6-12 hours (max) of duration; nebulizer delivers more, but greater side effects; oral is least effective (requires more dose --> side effects); can be used night symptoms, but not ideal

27

What is the class for Terbutaline (Brethine)

beta 2-selective beta agonist

28

What is the mechanism for Terbutaline (Brethine)

Agonist: beta 2

29

What are the therapeutics for Terbutaline (Brethine)

Prevent or reverse exercise-induced bronchospasm; mild asthma; COPD; early labor

30

What are the important side effects for Terbutaline (Brethine)

Can mask progressively severe inflammation