Sedative Hypnotic Drugs (M2)

Question 1

What are the main actions of sedative-hypnotic drugs?

Answer 1

1. sedation
2. relief of anxiety (anxiolytic)
3. Sleep (hypnosis)

Question 2

What is the term for the “relief of anxiety”?

Answer 2

anxiolytic

Question 3

What are equivalent barbiturates that are rarely used?

Answer 3

1. glutethimide

2. meprobamate

Question 4

What are the over the counter antihistaminic sleep aids?

Answer 4

1. diphenhydramine

2. doxylamine

Question 5

What is there a loss of that leads to narcolepsy?

Answer 5

orexin peptides in hypothalamic neurons

Question 6

When should sedative-hypnotic drugs not be used?

Answer 6

with inhibitors of P450 and liver dysfunction

Question 7

What kind of sleep pattern increases with hypnotic drugs?

Answer 7

NREM sleep (not as good as REM)

Question 8

What are the lipid soluble barbiturates that penetrate the brain and cause anesthesia?

Answer 8

1. Thiopental

2. Methohexital

Question 9

Which of the sedative-hypnotic drug groups has a minimal tolerance?

Answer 9

Z-drugs

Question 10

What are the three types of anxiety?

Answer 10

1. secondary to systemic disease
2. situational anxiety
3. pyschological

Question 11

What are the types antidepressants used to treat anxiety states?

Answer 11

1. Selective serotonin reuptake inhibitors (SSRIs)

2. Serotonin-norepinephrine reuptake inhibitors (SNRIs)

Question 12

What do you not take anxiety medications with?

Answer 12

other anti-anxiety meds (no combos)

Question 13

What age group is more sensitive to sedative-hypnotic drugs?

Answer 13

elderly

Question 14

On the scale from A-D and X, which letter corresponds to positive evidence of human fetal risk with the use of a medication?

Answer 14

D and X