Chemotherapeutic Drugs Intro (M3)

Question 1

What types of drugs does antimicrobials include?

Answer 1

1. antibacterial
2. antifungal
3. antiviral

Question 2

What are the two stages that chlamydia can exist?

Answer 2

1. infectious particles called elementary bodies

2. intracytoplasmic, reproductive forms called reticulate bodies

Question 3

What are the diseases that are associated with chlamydia?

Answer 3

1. trachoma
2. inclusion conjunctivitis
3. genital infections
4. respiratory infections

Question 4

What is the obligate intracellular gram negative bacteria found in ticks, lice,fleas, mites, chiggers, and mammals?

Answer 4

rickettsia

Question 5

What are the diseases associated with rickettsia?

Answer 5

1. rocky mountain spotted fever

2. epidemic and murine typhus

Question 6

Where do mycoplasmas affect the human body? 1. Are they capable of reproduction and colonization? 2. What are they resistant to? 3

Answer 6

1. respiratory and urogenital tracts
2. yes
3. penicillin

Question 7

What are the diseases associated with mycoplasmas?

Answer 7

1. Mycoplasma pneumonia

2. urethritis

Question 8

What is unique about fungi cell structure? 1. Where is their DNA contained? 2

Answer 8

1. internal membrane system dividing cell into regions

2. cell wall

Question 9

What are the two types of fungi?

Answer 9

1. molds

2. yeasts

Question 10

What type of fungi are single cells? 1. How does this type reproduce? 2

Answer 10

1. yeasts

2. budding

Question 11

What type of fungi are hyphae (branching tubules)? 1. How does this type reproduce/grow? 2

Answer 11

1. molds

2. branching

Question 12

What are the two types of protozoa? 1. What disease is associated with them? 2

Answer 12

1. trophozoites and cysts

2. acanthamoeba corneal infections

Question 13

What are the different classifications given to antibiotic drugs?

Answer 13

1. spectrum
2. cidal or static
3. deep or shallow
4. resistance
5. mechanism of action

Question 14

What are types of broad spectrum antibiotics?

Answer 14

1. chloramphenicol

2. tetracyclines

Question 15

What are types of moderate spectrum antibiotics?

Answer 15

1. sulfonamides

2. aminoglycosides

Question 16

What are types of medium and moderate spectrum antibiotics?

Answer 16

1. penicillins

2. cephalosporins

Question 17

What are types of narrow spectrum antibiotics?

Answer 17

1. macrolides

2. polypetides

Question 18

What is the antifungal used for superficial infections?

Answer 18

Griseofulvin

Question 19

What is the antifungal used for systemic infections?

Answer 19

polyenes (amphotericin)

Question 20

What are the antibiotics that affect bacterial cell wall synthesis?

Answer 20

1. Beta lactams
2. bacitracin
3. vancomycin
4. cycloserine

Question 21

What are the antibiotics that affect bacterial cell membrane permeability?

Answer 21

polypeptides

Question 22

What are the antibiotics that affect bacterial protein synthesis?

Answer 22

1. tetracycline
2. chloramphenicol
3. macrolides
4. linomycin
5. aminoglycosides

Question 23

What are the antibiotics that affect intermediary (folate) metabolism?

Answer 23

1. sulfonamides

2. fluoroquinolones (DNA synthesis)

Question 24

What are the antifungals that bind to cell membranes?

Answer 24

polyenes: amphotericin

Question 25

What are the antifungals that block thymidine synthesis, impairing DNA synthesis?

Answer 25

pyrimidines: flucytosine

Question 26

What are the antifunglas that impair synthesis of the cell membrane?

Answer 26

azoles: voriconazole

Question 27

What are the antifungals that target fungal cell wall by inhibiting glucon synthesis?

Answer 27

echinocandins: caspofungin

Question 28

What is common to all antibiotics and can be from mold skin reactions leading to anaphylactic shock?

Answer 28

hypersensitivity phenomena

Question 29

What happens if susceptible microflora of the GI tract are altered by the use of oral meds?

Answer 29

superinfections