(3) Exam 3-❤️ Lecture #2- Coronary Artery Disease & Angina Flashcards
Coronary Artery Disease
In CAD, what happens to fatty deposits over time?
They harden
Coronary Artery Disease
🚬 CAD is the leading cause of death in what gender?
Females
Coronary Artery Disease
“Hardening of the Arteries” is another name for what disease?
CAD
Coronary Artery Disease
What is Atheromas?
Fatty Deposits
Coronary Artery Disease
What is a major cause of CAD that is characterized by lipid deposits within intima (inner lining) of the artery?
Atherosclerosis
Coronary Artery Disease
What plays a major role in the development of fatty deposits that get under the endothelial and build up plaque?
Inflammation
Coronary Artery Disease
💉 What is nonspecific marker of systemic inflammation that isn’t specific to the location of inflammation but tends to indicate CAD when the results are high?
C-Reactive Protein (CRP)
Coronary Artery Disease
🚬 What is the #1 cause of chronic injury that results in fat and plaque build up over time to become a major blockage?
Hypertension
Coronary Artery Disease
🚬 Two or more of what problems will cause the development of CAD?
▪️Hypertension ▪️Tobacco Use ▪️Diabetes ▪️Infections ▪️Toxins
Coronary Artery Disease
♿️ The artery has its own capillaries and blood supply so when there’s a tear in the lining it starts to bleed and develops a blood clot in the blood vessel that causes what complication due to the artery being locked?
Heart Attack
Coronary Artery Disease
When there is a slow build of plaque and not enough oxygen, what can develop that causes small blood vessels around the heart to incease their blood flow and the growth of new blood vessels to supply the ischemic area with blood flow?
Angiogenesis
Coronary Artery Disease
If there is a massive coronary artery blockage, what may protect from an infarction by still supplying adequate blood flow to the heart muscle?
Collateral Circulation
Coronary Artery Disease
When may collateral circulation be inadequate causing a heart attack to occur?
Rapid onset of CAD. Blood clot develops rapidly
Coronary Artery Disease
🚬 Increased risk for CAD occur at what age for men and woman?
Men >45 years
Woman >55 years
Coronary Artery Disease
🚬 Men have more CAD until woman reach what age in which it becomes equal for both genders?
Woman reach age 55
Coronary Artery Disease
🚬 African Americans have a higher mortality but what ethnicity has the highest incidence?
Caucasians
Coronary Artery Disease
🚬 What ethnicity have heart attacks at a younger age and double the mortality compared to the rest of the population?
American Indians
Coronary Artery Disease
🚬 What ethnicity have a very low incidence of CAD and a low mortality rate?
Hispanics
Coronary Artery Disease
🚬 What has a major contributing component and is the #1 modifiable risk factor for CAD
Elevated Serum Lipids
Coronary Artery Disease
🚬 What cholesterol levels increase the risk for CAD?
> 200 mg/dL
Coronary Artery Disease
🚬 What Triglyceride levels increase the risk for CAD?
> 150 mg/dL
Coronary Artery Disease
🚬 What LDL levels increase the risk for CAD?
> 160 mg/dL
Coronary Artery Disease
🚬 What HDL levels increase the risk for CAD in men and woman?
Men >40 mg/dL
Woman >50 mg/ dL
Coronary Artery Disease
🚬 What BP puts someone at high risk for CAD?
140/90
Coronary Artery Disease
💊 What is treatment for patients with prehypertension?
Lifestyle changes?
Coronary Artery Disease
💊 What aggressive treatment is used for patients with stage 1or 2 hypertension?
Medication and lifestyle modifications
Coronary Artery Disease
🚬 What 3rd highest risk factor for CAD↑HR BP due to vasoconstriction, ↑LDL, ↓HDL, ↑Oxygen Radicals, and ↑Carbon Monoxide?
Tobacco use
Coronary Artery Disease
🚬 What is not a high risk factor for CAD but tends to go along with physical inactivity?
Obesity
Coronary Artery Disease
🚬 What are the top 4 modifiable risk factors for CAD?
1) Elevated Serum Lipids
2) Hypertension
3) Tobacco Use
4) Physical Inactivity
Coronary Artery Disease
🚬 Waist circumference >40” in men, >35” in woman, or a BMI greater than what increases the risk for obesity?
BMI >30
Coronary Artery Disease
🚬 Because diabetes is a risk factor for CAD, A1C should not be greater than what percentage?
Don’t want it > 7%
Coronary Artery Disease
😷 When encouraging lifestyle changes, what realistic goals do you want to set with the patient to achieve risk reduction?
Pick one of the big four modifiable risk factors for the patient to work on. Don’t be unrealistic and suggest multiple changes.
Coronary Artery Disease
📚 A physical fitness plan using the FITT formula recommends how many minutes of aerobic exercise most days of the week plus weight training 2 days per week for patients with CAD
30 mins
Coronary Artery Disease
🍓 Any fat that comes from an animal has what in it?
Cholesterol
Coronary Artery Disease
🍓 A decrease in what dietary changes should be recommended to patients with CAD?
↓Saturated fats & Cholesterol
Coronary Artery Disease
🍓 Patients with CAD should decrease the consumption of what specific foods that come from animals?
↓Red Meat, Egg Yolk, & Whole Milk
Coronary Artery Disease
🍓 What dietary changes should be increased in patients with CAD?
Complex Carbohydrates, Fiber, & Omega-3 Fatty Acids.
Coronary Artery Disease
🍓To increase complex carbohydrates in patients with CAD, complex carbs such as candy and maple syrup should be avoided and what foods containing starch should be suggested?
Potatoes and Beans
Coronary Artery Disease
🍓 Patients with CAD should be taught to increase or add chia seeds, nuts, and what fatty fish in their diet to increase Omega 3-Fatty Acids?
Sardines
Salmon
Tuna
Mackerel
Coronary Artery Disease
🍓 In patients with CAD, most of the fat intake should be from what type of oils?
Vegetable Oils (olive, safflower, corn, soybean, flaxseed, cottonseed) or oils in nuts.
Coronary Artery Disease
🍓 Patients with CAD should reduce their fat intake to what percent with most from monounsaturated fats and less from saturated fats?
25-35%
Coronary Artery Disease
💊💥 What type of drugs are initially started if diet and exercise doesn’t effectively lower lipid levels?
Statins
Coronary Artery Disease
💊💥 Zocor is what type of drug given to patients with CAD to increase cholesterol synthesis, decrease LDL, and increase HDL?
Statin
Coronary Artery Disease
💊💥 What Statin drugs is commonly given to patients with CAD when diet and exercise are not effectively lowering lipid levels?
Zocor (simvastatin)
Coronary Artery Disease
💊💥 When the patient is prescribed Statin drugs, what is initially monitored and rechecked with any increase in dosage?
Liver enzymes
Coronary Artery Disease
💊💥 Statins, Niacin, Fibric Acid, Bile Acid Sequestrants, and Cholesterol Absorption Inhibitors are what type of drugs used in patients with CAD?
Lipid-Lowering Drugs
Coronary Artery Disease
💊💥 What Lipid Lowering drug↓LDL, and↑HDL?
Statins
Coronary Artery Disease
💊💥 What Lipid-Lowering Drug↓LDL,↓Triglycerides, and↑HDL?
Niacin
Coronary Artery Disease
💊💥 What Lipid Lowering Drug↓triglycerides and↑HDL?
Fibric Acid
Coronary Artery Disease
💊💥 What Niacin drug is a high dose B Vitamin?
Niaspan
Coronary Artery Disease
💊💥 What Lipid-Lowering Drug has side effects of Flushing, Pruritus, GI side effects, and Orthostatic Hypotension due to vasodilation?
Niacin (Niaspan)
Coronary Artery Disease
💊💥 The Lipid-Lowering Drugs Niacin, Fibric Acid, and Bile Acid Sequestrants all have what common side effect?
GI side effects
Coronary Artery Disease
💊💥 What is the most common Bile Acid Sequestrant used for Lipid Lowering Drug Therapy?
WelChol (colesevelam)
Coronary Artery Disease
💊💥 What Lipid-Lowering Drug binds with other drugs so must be taken separately from other drugs?
Bile Acid Sequestrans - WelChol (colesevalam)
Coronary Artery Disease
💊💥 What Lipid-Lowering Drug increases conversion of cholesterol so that it can be excreted through the feces?
Bile Acid Sequestrans - WelChol (colesevelam)
Coronary Artery Disease
💊💥 What Fibric Acid Derivative is commonly given as Lipid-Lowering Drug Therapy?
Lopid (gemfibrozil)