(2) Exam 3- Pancreas Flashcards
Acute pancreatitis
In the United States, what is the most common cause of injury to the pancreas
Gallbladder disease
Acute pancreatitis
What ethnicity is three times more likely to have pancreatitis
African Americans
Acute pancreatitis
Biliary sludge is a mixture of
Cholesterol crystals and calcium salts
Acute pancreatitis
What is the most common pathogenic mechanism of acute pancreatitis
Autodigestion of the pancreas
Acute pancreatitis
What is autodigestion of the pancreas
Pancreatic enzymes are activated in the pancreas rather than in the intestines
Acute pancreatitis
What is an in active proteolytic enzyme produced by the pancreas
Trypsinogen
Acute pancreatitis
In the small intestines, trypsinogen is activated to
Trypsin
Acute pancreatitis
In pancreatitis, activated trypsin in the pancreas can digest the pancreas and produce
Bleeding
Acute pancreatitis
Clinical manifestations
What is the predominant manifestation of acute pancreatitis
Abdominal pain
Acute pancreatitis
Clinical manifestations
In acute pancreatitis, in what quadrant is abdominal pain usually located in and because of its retroperitoneal location where does the pain radiate
LUQ
Commonly radiates to the back
Acute pancreatitis
Clinical manifestations
In acute pancreatitis the pain has a sudden onset and is described as
Severe, deep, piercing, and continues or steady
Acute pancreatitis
Clinical manifestations
In acute pancreatitis does eating relieve or aggravate the pain
Pain is aggravated by eating
Acute pancreatitis
Clinical manifestations
In acute pancreatitis is pain relieved by vomiting
It is not received by vomiting
Acute pancreatitis
Clinical manifestations
In acute pancreatitis, the pain may be accompanied by
Flushing, cyanosis, dyspnea
Acute pancreatitis
Clinical manifestations
Bowel sounds an acute pancreatitis
Decreased or absent
Acute pancreatitis
Clinical manifestations
Other manifestations of acute pancreatitis
Nausea and vomiting, low-grade fever, leukocytosis, hypotension, tachycardia, jaundice, abdominal tenderness with muscle guarding
Acute pancreatitis
Clinical manifestations
What circulating enzyme causes intravascular damage resulting in areas of cyanosis or greenish to yellow-brown discoloration of the abdominal wall
Trypsin
Acute pancreatitis
Complications
What are two significant local complications of acute pancreatitis
Pseudocyst and abscess
Acute pancreatitis
Complications
What are the manifestations of pseudocyst
Abdominal pain, palpable epigastric mass, nausea, vomiting, and anorexia
Acute pancreatitis
Complications
Serum amylase level with pseudocyst
Elevated
Acute pancreatitis
Complications
What are the treatment options for pseudocyst
Surgical drainage, percutaneous catheter placement and drainage, endoscopic drainage
Acute pancreatitis
Complications
What is a pancreatic abscess
Collection of pus
Acute pancreatitis
Complications
Where the manifestations of an abscess
Upper abdominal pain, abdominal mass, high fever, and leukocytosis
Acute pancreatitis
Complications
To prevent sepsis, what is required with pancreatic abscesses
Surgical drainage
Acute pancreatitis
Complications
The main systemic complication of acute pancreatitis are pulmonary and cardiovascular complications and tetany caused by
Hypocalcemia
Acute pancreatitis
Complications
When hypocalcemia occurs, it is a sign of
Severe disease
Acute pancreatitis
Complications
As a result of Intraabdominal hypertension and edema, patients with severe acute pancreatitis at risk for
Abdominal compartment syndrome
Acute pancreatitis
Diagnostic studies
What is the primary diagnostic tests for acute pancreatitis
Serum amylase and lipase
Acute pancreatitis
Diagnostic studies
Sarah and Emilyβs level is usually elevated early and remains elevated for
24 to 72 hours
Acute pancreatitis
Diagnostic studies
Serum lipase level, which is also elevated in acute pancreatitis, is an important test because
Other disorders may increase serum amylase levels
Acute pancreatitis
Diagnostic studies
What is the best imaging test for pancreatitis and related complications
CT scan
Acute pancreatitis
Diagnostic studies
In acute pancreatitis, serum amylase, serum lipase, urinary amylase, blood glucose, serum calcium, and serum triglycerides are elevated except
Serum calcium
Acute pancreatitis
Collaborative care
Goals of collaborative care for acute pancreatitis
1) relief of pain
2) prevention or alleviation of shock
3) reduction of pancreatic secretions
4) Direction of fluid and electrolyte imbalances
Acute pancreatitis
Collaborative care
Treatment is primarily focused on
Aggressive hydration, pain management, management of metabolic complications, and minimization of pancreatic stimulation
Acute pancreatitis
Collaborative care
What medication may be used to control pain
IV morphine