Alchol liver disease Flashcards

(47 cards)

1
Q

weekly recoomned units for men and women

A

14

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2
Q

is Gamma- glutamyl transpeptidase raised or lowered in liver disease

A

raised

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3
Q

time taken for alchol withdral syndomre after last drink

A

24 to 72 hours

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4
Q

symptoms of alchol withdrawl

A

Sweating
Tachycardia
Hypertension
Anxiety
Headache
Insomnia
Visual hallucinations
Weakness
Nausea
Retching
Vomiting
Seizures

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5
Q

what are benzodiazepine examples

A

diazepam, chlordiazepoxide or lorazepam

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6
Q

what drug treatment is needed for wirther of alchol

A

benzodiazepine and thipaine (b1)

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7
Q

is depression alsong encephglogctoy

A

yes

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8
Q

highest alchol morbity nation in uk

A

scotland

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9
Q

what is the intermedialy of alchol absobsiton

A

acetaldehyde

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10
Q

how is ethanol convred to acealdehyd

A

though nad, to nahd by alhcol dehydrogenase
or
nadph to nadp+ by cytochrome p4502e1

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11
Q

how s acetaldehyde turned to acetate

A

by nad, to nahd though acetaldehydae dehydrogenase

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12
Q

what is the dangeer alchol chemcial for liver

A

increased acetyldeh hydrate
and increas in nadh ration

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13
Q

what is steatotois

A

fatty liver disease

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14
Q

what is steatohepatisis

A

fatty liver with inflaiton
neurophiliic inflation
fibrosis, cirrhosis, build up of scar tissue

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15
Q

what is the cage questionalr for alchol

A

cut down alchol- ever felt need to
Annoyed - by someone cirtisied your during
guilty - about drinking
eyeopner - do you need one

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16
Q

how many units of alchol are in
a - glass of wine
b - shot
c - normal cider/ beer/ larger
d - bottle of wine

A

a - 2
b - 1
c- 2
d - 9

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17
Q

what score of fast is an immediate stop

A

3 or 4

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18
Q

first quetion on fast

A

having more than 6 units female or 8 unit male on single occasion

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19
Q

what are te cut off vales ofr the audio queson scoring for alchol

A

0-7 low risk
8-15 increasing risk
16-19 high risk
20+ possible dependence

20
Q

signs of chroci liver diease on hands

A

leukonychima, dupuytens contracure, hepatic flap, clubbing, palmar erythema

21
Q

general signs of alhcol liver disease

A

skin pigmentation
loss of hair
brusing
cachexia (muscle waisting)

22
Q

what are the chest signs of alcholic liver disease

A

gynaemaosiam, breast atrophy, spider neuvid

23
Q

what are the testiclar signs of alchol liver disea

24
Q

what are the face signs of alcholic liver diseaw

A

jaunice, parotid gland enlargement
xanthelsma

25
what are the leg sings of chic liver diseas
scratch marks and odema
26
what ar teh abdomial signs of chrnic liver disease
asceites, hepatomelagly, dialted umbillac vessles , splenomegaly
27
what are the lab finds for alchol ilvier disease
aat >alt rasied gamma glutamyl tranferase macrocytosi trhombocytopenia
28
what does gamma glucatml tranfaere indicate
liver or bile duct damage
29
what are the 4 grades of hepatic encephalopathy
1- mild confusion 4- comatosed
30
caues of hepatic encepholoapgy
infection, drugs, constiapation, gi bleed, electorlyte distubance
31
what are alternative diagnos for hepatic encephaolpathy
infecton, hyypoglycaemia, intracrainal bleed
32
treatment fo hepatic encephalogpy
bowwl clear out, laculsoe, enema, antibioci, itu, airway suppor, ng tube for meds
33
what are the symptons of sponateus bacterial peritoneis
abdomal pain, fevour , rigos, renal imparime , sepsi, tahcaria, temp
34
why do you tap sponatsu bacterial peritonitis
fluid prion adn glucose levles cutlres white cell count
35
treatment for spontaous bactial periotnais
iv antibioc ascitic fluid drin iv albumin infusion
36
what is acute bactieal periotnsi
acute infeiction of asciteis
37
presntaion of alcholic hepatis
jauicne, encephalopathy, infection, decopais hepatic fucniton
38
sings of decomapti hepatic fucton
low albumin and rised prothorbin time
39
change in biochemcial in alhcol hepatis
raised bilirubin, riased ggt and alkp
40
treatme for alcholic hepatis
supportive treat encepaholy trat alchol withdraw protect against gi bleed protect airway
41
tratme fo ralchol withde
bendodiapiens
42
what grade on the galsgow alcholidd hepatisi score do you need for sternodi to be worth it
9 or hgiher
43
what grade do you need to be on maddrey discriment fucniton to treat with oral steroids
32
44
how to offer ntuion for alcoli hepatis
ng tube with high nution frequent feeds
45
benfiit of nutrion in alhcolhepis
changes 2 year survi form 15% to 70%
46
what are the cause of fatty liver diseae
obesity diabes hypercholsia
47
signs of steathopais
raised alanine amio transfase fatty fliver on uss