Liver Symposium

Question 1

what type of virusse are hep a and e

Answer 1

enteric virues

Question 2

what type of virus are hep, b, c and d

Answer 2

parenteral virues

Question 3

enternic virus meaning

Answer 3

infect gi mucosa

Question 4

parental virus meaning

Answer 4

a virus which is transmitted though a route other than the gi tract i.e. sexual transmiaon

Question 5

waht type of virus is hep a

Answer 5

rna virus

Question 6

what is the transition of hep a

Answer 6

faecal - oral , sexual blood

Question 7

what age group is most associated with hep a

Answer 7

5-14 years

Question 8

how to detect hep a

Answer 8

igm antiboides

Question 9

who is immunised against hep a

Answer 9

travellers, patients with chronic liver disease, haemophilic, occupation exposure - lab workers, men who have sex with other men

Question 10

What are the side effects of hep a

Answer 10

cholestasis (pruritus, significant jaundice, dark urine and pale stools)

Question 11

What is the general presentation of hepatitis

Answer 11

Abdominal pain
Fatigue
Flu-like illness
Pruritus (itching)
Muscle and joint aches
Nausea and vomiting
Jaundice

Question 12

what is the stucure of hep b virus

Answer 12

a dna centre which is double straned , with many outer lippinged counting to with hb servfe antigens to stop detionetion

Question 13

how is hep b transmitted

Answer 13

sexual, ivdu, toother brush, razor, contact with open cuts , pregnancy transfer - vericla transmission

Question 14

what pernet o poeple with hep b recover

Answer 14

85%

Question 15

what does the hepatisu surface antigne signifiy

Answer 15

presence of the virus,

Question 16

what ode shte hepatis e antigne signify

Answer 16

active replicaiton

Question 17

what does hte heaptice core antigen disfiy

Answer 17

acive repaltion (this cannont be deteced in blood) - this couleb be past or currne tinfeciotn

Question 18

what does the hep b bna foundin blood signify

Answer 18

active replicatoin

Question 19

what does hte anit bs antig show

Answer 19

protection ie from previosu infection or vaccintation

Question 20

what does hte igm anti hbc show

Answer 20

acute infection

Question 21

what does hte igg anti hbc show

Answer 21

chronci infection/ exposure

Question 22

what does ht fanti hbe show

Answer 22

inactive virus

Question 23

what treatmen is done for hbsag potive

Answer 23

look for igm anti hbc

Question 24

what are the outcoem for hep b

Answer 24

no fuerh progaion
cirrhosis
hepatocelluar carinoma
end stage liver diase

Question 25

waht antigen is given in hep b vaccination

Answer 25

hbsag

Question 26

what is inclued in management for hep b

Answer 26

screening for other viral infections such as hiv, hep a,c and d avoiding alcohol education about transmion contract tracing testing for compilation i.e. fibrosacn for cirrousi antiviral medication pegylated interferon liver transpaltion

Question 27

benifit of telivudine tratment for hep b

Answer 27

leads to no resiatn bacteria strains

Question 28

what type of virus is hep c

Answer 28

rna

Question 29

how is hep c frpead

Answer 29

blood and boddily fluida dn sex

Question 30

how is he c cured

Answer 30

direct acitign antivurla medication e.g. sofosbuvir and daclatasvir

Question 31

what paercent of pele develop chroic hep c

Answer 31

75%

Question 32

what are complicaions of hep c

Answer 32

liver cirrhosis, hepatocelluar carinoma

Question 33

what ar the tests for hep c

Answer 33

hep c antibody screening, hep c rna testing

Question 34

what type of virus is hep d

Answer 34

rna virus

Question 35

whihc virus does hep d need to live

Answer 35

hep b as it needs the hbsag

Question 36

treatmen for hep d and lenght

Answer 36

pegylated interferon alpha over 48 weeks

Question 37

dangers of hep d

Answer 37

makes all hep b problems worse

Question 38

what type of virus is hep e

Answer 38

rna

Question 39

what is the symptosm of hep e

Answer 39

very mild and only last one month can very raley cause hepatis and live failure in immunocompromised paitesn

Question 40

what is the hep g realed to

Answer 40

hcv

Question 41

what is the treatmen for parfcetla induced liver failure

Answer 41

n acelty cystin infusions

Question 42

what exnme cuaes hte n aceyl p benzqoium inie that is toaxi to pbe prouced

Answer 42

cyp450 systems

Question 43

what is the issue with paracentla ob=verudoe

Answer 43

glutahoimone is not enough to remove excess toxic substance

Question 44

what are the 3 types of non alcholic fatty liver disease

Answer 44

simple steatosis non alcholic steatohepatitis fibrosis and cirrhosis

Question 45

risk facots for nafld

Answer 45

age, efnicy , genciec e.g. pnpla3 gene

Question 46

what percent of pele with nafld develop steatosi

Answer 46

30%

Question 47

what is simple steatosis

Answer 47

harmles buildup of fat in liver cells

Question 48

what is non alcholic statohapatis

Answer 48

build up of fat that leads to inflation nd scarring

Question 49

path way sof nafld

Answer 49

normal livr to statosis, to statohapatis and then cirrhosis

Question 50

chemcial tests for nafld

Answer 50

enhanced livr fibross panel, hyaluonic acid, timp and piinp ast/alt raction cytokeratin 18 - marker for infection

Question 51

what scans are done for nafld

Answer 51

mr/ct, firboscan, ultarions, mr spectoscopys, liver biposy

Question 52

what is the nf score made of

Answer 52

age, diabetes, bmi, ast and alt ratio, pltlet cound, albumin

Question 53

what level is nafld score a high risk

Answer 53

above 3

Question 54

what makes up fib 4 score

Answer 54

age,ast lelve, platatle cound and alt

Question 55

below what score show no fibrosi for fib 4

Answer 55

1.45

Question 56

above what score fshow cirrhos for fib 4

Answer 56

3.25

Question 57

treatmen for nsadi

Answer 57

diet and weight reaction, exercise, insuline sensitzer e.g. metformin or pioglitazone, gluagon like pepdies analogs, farnesoid x nuclear receptor ligah vit e weight reduction surgeries

Question 58

which gender is autoimmune hpatpis mainly in

Answer 58

fmeale

Question 59

what is elevated in aueimmuen hepatis

Answer 59

igg

Question 60

what are the types of autoimmune hep

Answer 60

1 - ana, sma, 2 - lkm1 3 - sla

Question 61

how to diago autoiummen ehp

Answer 61

liver bipsy

Question 62

treatmetn for ausotiume hep

Answer 62

steroid and long term azathioprine

Question 63

what gender is amily effected by piarmy bilary cholangits

Answer 63

femagles

Question 64

what is elaved in primary bilary cholangits

Answer 64

igm and anti micobial antibody

Question 65

waht is effected in pairjmy bilary cholangits

Answer 65

intrahelpic bile duct

Question 66

what gender is piarmy schlerosing cholagnits

Answer 66

males

Question 67

what is postive in primary scholerosing cholangits

Answer 67

Perinuclear antineutrophil cytoplasmic antibody (p-ANCA) Antinuclear antibodies (ANA) Anti-smooth muscle antibodies (anti-SMA)

Question 68

what type of disease is priamry schlering choholangits

Answer 68

stircute diseaes

Question 69

signs of pmariy schligsn cholsign

Answer 69

recureng cholagit and jaundince

Question 70

treatment for piamry scholign choladn

Answer 70

bilary stn if one artery envolvemtn

Question 71

why do we transplant

Answer 71

chronic livr disaes with poor prediced survical, poor quailty of live, heapatocllar caricmoa, acure liver failure, gendti disease e.g. oxaluria and tyromia

Question 72

contraidicaiotn for liver transplant

Answer 72

extraheaptic maligancy, hepatic maligacy with macrovasualr or diffuse tumore invasion, active and uncontroeled infection outside of the hepatobillary system, active substance and alcohol abuse, sever cardiopmary or other co mordi condion, pycoclal factors which would reclude recover y after transalt, techial or anatomcy barris, brain death

Question 73

how to prioritise in alf

Answer 73

ph, inr, arteal lactate, encephalopathy, age, jaudince to encpaty interval

Question 74

socring systms for cirohso

Answer 74

chils, meld , ukeld

Question 75

what is the psot opperative drus for over transpaln

Answer 75

sterois, azathiopinre, taclimus and cylosporine