Inflamatory bowel disease Flashcards

(69 cards)

1
Q

conditsion included in ibd

A

chrones, uc and microcpic oloitns

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2
Q

where does uc start and psread to

A

rectum and spreds proximmary but is contiane in colon

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3
Q

where is chones found

A

it is found in patches anywehre in the body,

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4
Q

what is when you have both uc and chrones

A

it is ibdu - unclaise inflatioary bowol disease

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5
Q

what is the two types of microscopci bowel disease

A

collangous colits and lympathcoic cytis

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6
Q

who is colangous colanits mainly seen in

A

females

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7
Q

what are the sympons of collangeous colonitis

A

belly pain
watery diharrea

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8
Q

cause of collangous colantis

A

inflatmo of the cell, reduice the absoaptonof water due to thicekn of eptilum

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9
Q

wha tis lympathic coltois

A

increas in lympathc cell

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10
Q

what is lympathc colotis asosiced with

A

meds such a sppi and ns aids
auto immune conditions such as rhmaoid artheris and celiac disease

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11
Q

symptons of lymphocytic colitis

A

dirahes and abdoal pain, simlar to collangeous colitis

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12
Q

treatmetn for lymphoticy colits

A

budenidies

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13
Q

does smokng increase risk for chones or uc

A

increase risk for chrones
reuces risk for UC

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14
Q

symptons of ibd

A

diahre, rectal bleeding, weight loss, fatique and abdomal pain

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15
Q

what bacteira are presnt in ibd more than in nroaml immenune system

A

acinobacteria and proteobacteria

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16
Q

what bacteira is presnet less in ibd

A

bacteroidets and lachnospiracease

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17
Q

what is the average age for uc

A

20 - 40

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18
Q

what is the symptson of uc

A

bloody diarrhoea
abdomal pain
weight loss
fatique

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19
Q

what area if inlfatin in procitis

A

rectum only

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20
Q

wjat area is inflatiend in procisgnitis

A

recutm and sigmoid col

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21
Q

what area is inflaed in left side colholits

A

all of hte left side of the colon

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22
Q

what area is inflated in pancolitis

A

whole colon

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23
Q

sympons of procitis

A

freqycl urgen, incotin an tenesums
blood
proxla faecl status constiapion

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24
Q

how to treat procitsi

A

topical therpaty

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25
what is acute severe colitis
life threatening meidcial emercey with high mortaily of 2%`
26
scale of severity fo uc
mild less than 4 stools per day, with or with blood, normal esr, no sight of toxicity moderate - 4- 6 stools per day, occasaioal blood, minla sings of toxicity , reduced crp severe colitis , 6 or more blood stool, and any of , raised temp , tachycardia, anemai esr and raised crp fulmainat - 10 stools per day, contius bleeding, toxicity k abdal tendersns or distion, tranfusion requice, colic dilation on x ray
27
bloods fuction in uc
inflamation marker, normocytic microcytic anemai crp, wcc platlels, incrased albumin reudced
28
stool test for uc
look for calprotecign and cultrue for incetion
29
colonsocpy for uc
to look for maliganyc and polyops
30
what is 1 and 2 on brisl tsotl tat
1 rabbit droping 2 - saus sheped byut lumps
31
what is type 3, 4 and 5 on bristol stool chart
3 - sausage with cracks on surface 4 - sausag or smake and smoth and soft 5 - soft blobs with clear out edges
32
what is 6 and 7 on bristol stool caht
6 - flffy pcies with ragged edge 7 ligquid
33
tests for acute sever coloitsn in first 24 hours
blood tests stool chart 4 cidf cultres
34
drug tramtesn for first 24 hours for colitis
avoid / stop non sterold analgsi, opidaes, and dihrsl ant coholanse iv glucocorticoids, iv hydration
35
what is the sympoosn of choroens disease
diharrheoa, abdomal pain, weight loss, malsais, lethary, anoxia, low grade fever, malabsobition, anemai, vi deifion
36
blood for chornes
look for inflations
37
stool for crones
to rule out infection if dihrar and fecla claproteicino
38
what level of felauproic is normal, equivola nd elevated
0-50 nroal, 50 -200 equivol , greater than 200 raised
39
what scan are done for crones
capusl endocpys, colonsocpy, mri small bowel stuy, occasional ct scan if acutly unwell
40
what is the differen in histolgy bwtwen crones and uc
uc - goblet cell deped greater cyrpa abcess limited to mucoa cd - tranmulra infalton granumlomas
41
what are some stucla complication ue to chroesn
inflation sticure fistula
42
what is perianal choens disasesympons
unable to sit pus secretion perianal pain
43
investigation for perianal crohns disease
mri pelvis examion under anemaiths
44
treatment for perianal choens
surgyer to drain it and put stent in place medicaiton
45
extrainteal manfiion of ibd
mot ulcer, skin / lesion, mucaion erthy nodum, pydodrl gancer, parim sclerous cholangitws
46
cuase of choicn digrea
malabopoi e.g. pancreai inusigo or biel acid malabion, coleica diase, ibs, overflow diarra
47
why does biel acid malbaion cause dihora
as bile acid is an laxative
48
what are other diffencatno for ibd
ileocacel tb, coltiis, invfacein, amoberi, ishcmic
49
who is most at risk fo rcolonic carcina
pancolits and those who have it for longest
50
how oftne should low risk, medu risk and high risk people with adenocarino have colonsocpy from 10 years of onset of disease
low - 5, medium 3, high 1 year interval
51
treatment pyimad of ibd
5 asa / sulfaszalide predinsone or budensoid immuno modulatrs biologic gaens surgery
52
what is amiosaclicyates exampels
penseate which work on small bolw
53
can 5asa be used in choesn
no , only effect in uc
54
how can 5asa be used
orally dialy during flairups rectal topically
55
who can recive steroid
both uc and cd
56
common steroid
budesonid and prenosale
57
what is required of rprenisole
calcium and vid d supplement
58
what can metoterxate be used for
choesn only
59
issue with methotreaat
it is a tetartogenic
60
hwo qalify for methotrexate
steroid dependednt paitiens
61
who can methoga be used on
crones only
62
what are hte monc cona antiboids which can be used
infliximan - anti tnf alph antib 8 wekk iv infion
63
new treatm for ibs
tonacinib, pan jak inahtor and is used orally
64
how to give inflimab
8 weekly iv infuions
65
what is the preiclp of elemtal feeding
feeding of only certain food snad othering else, non effecig in adults
66
what is emergy cusry requied for ibd
acute sever colitis athat is not resond to high dose iv setoids complatio such as perforation, absfes and fobsution
67
what is the elective surgyer for in ibd
frequent relapse despite medical treatment not able to tolerate medical treatment steroid dependant patient choice
68
what is hte pouhc sueryg
wher the rmain reculaa stump can be use as a pouch to soer feauces
69
wha is the downside of the pouch
it can lead to severla times per day need to go to toiled can become infelcteld and inlfamed can have obstions