gut microbiota Flashcards

(61 cards)

1
Q

time taken for food to go form mouth to oesphagus

A

1 min

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2
Q

tie taken food is in oesphagu

A

4-8sec

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3
Q

time taken food is in stomac

A

2-4 horus

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4
Q

time foodn in sin smallninsts

A

3-5 hours

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5
Q

time of food in colon

A

10 hours to severla days

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6
Q

where is most of the bacteria in the gi travct

A

colon

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7
Q

bacteria found in mouth

A

streptococcus
anticnomyces
veilloneall
fusobacterium
porphromona
prevotella
treponema

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8
Q

common bacerai foudn in stomahc

A

lactobacciuls
candida
streocouccus
h pylor
peptostreococcus

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9
Q

common bacteira found in duodenu

A

stretococcus
laptobaccilus

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10
Q

common bacteira found in jejunum and proximal illeum

A

streptococcus , lactobacilllus

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11
Q

common bacteria foudn in distal illue

A

clodstidum
strepotcocsu
baceroides
acintomycinase
coryneactaisea

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12
Q

factors which cchagne hte gut micorbia

A

type of food - solid, formaular fhalthfood, inguriedes, whre it is form
antiboic treamtn
malnution
obses
age

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13
Q

fucntion of gut mboaita

A

defects agian pahtesn, tough ph inhiobt and barrier
modifes hosts section e.g. mucin and bile
metaboels of diteary compenos
produion of esserion metabolism
development f immune system
host signal - gut to brain axis

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14
Q

what are food which is bad for gut mciobisn

A

junk food

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15
Q

food whih si good for gut micorbison

A

fiber, i.e. plants, flut vegiaons, whore garins,

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16
Q

benifits of high fireb diet

A

imporve falce buliking reuling in an easire passesage
impiortan phyto chmea nd antioxian and fitamens
used fo rbacteiarl fermaiton, to help maintain ph, increase commnelaa bactal population, supply of short chain fatty acids

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17
Q

what is the stie of the most fermaitn of gut

A

cecum and ascingn colon

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18
Q

what is the ph in ascneg colon

A

mildy acidic

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19
Q

what is the main fucnitons of the right side of colon

A

shot chain faty acid and carbohyarte abostopon and metaboims

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20
Q

what is the fuciotn of the left side of the colon

A

slow utnrove rand liftel fuciotne ot hte carbosph mainly protein produciont

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21
Q

ph of descing colon

A

neutral

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22
Q

what is the harmful chemical found in desidng colon

A

nyh3 , h2,

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23
Q

what are the 3 main scfa needed in colon

A

buyrate
propinoate
acetate

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24
Q

acetate -

A

used fo rlipogneis and tranplorted in blood to peri;phaeral tissues

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25
propionate
gluconeogenis in liver satiety signalling
26
butyrate
intestinal peithel cell gorwht and regenationa
27
wher is most gi disseasi in colon
in distal colon due to higher ph and more harmful chemical s
28
does baceira fermaion lower ior incerase ph
lower ph
29
products of bacerial fermation
insulin, statch, lactae, and actaltate
30
what is sected in reposen ot acetat en proinate
glp 1 secteion wihc inhibs fat accumulation
31
what is the rulsut of propiaon adn butyrate
pyy secion , which improes insulin reisant and satiety signaling to brian
32
what is a ruls of butyrate
conic inflaitona nd carcinogneis - antiinlaiotn cyctokinesase
33
role of outer mucus layer
barrier effect, commensial bacteir close ot epitlh black adn prvets adhesi of pathsgens
34
role of inner mus layer
prevnet bacteria pentetion
35
epitheal layer reolw
if the bacteir pentre hte inner mus layer they are killed by the immeun systme
36
barrier effect of baceria
due to the sheer number of baceria close to the prevnet colonisaiton by ingested pathogens and inhibit gorwh of portely pathogneic bactirea
37
active competive exclusion
conferred by oth micorbe - microb and micrbon to host interacotin
38
what are cns disease linke o gut micobitoa
autiism specutm diagios depressive disored ms
39
what are gi disored likned to micorbia
ibd ibs nafld cirrhosis
40
what are the metabolism disroed linked to microbome
insulin reisance metabolic syndoem obesity cvd
41
what immunity disroedr sare associed with the micorbioe
allergies autoimmune disease cancer immuotharpy
42
how does hte gut microbia in ibd
reduced bacteiral diverisy
43
down side of ibd on micorbia
incraed diarrhea, and decreadd diesre for fibre
44
effect of bacterial compoin on microb
kill comensla baciera
45
is the effect of different antiboics differnet
yes, vancomyin is mroe powerful than clindamycin and it is more powerful then coproflaxin
46
what is the genral cahnge in baceria afer antiboi
firmicutes, and bacterides declina dn protetocabcteia increla
47
downside of protbacires
Pro inflmatory
48
downside of c diffe after antiboic thapry
it opens other neices follwoing antiboic shtapry, thus incrs in gorwn cuase toin rodunion, abdo pain andf fvever some staings are antiboics resiant
49
how does fecal microbla transport work
fecal sample form screened healthly donor transplanted into recpiant donor mcrobia repopulates large inteisns, displaces c diff, prevents reinefection
50
what percent of fmt is effect in c diffe
90%
51
effect of scfa on reudcion in carbohdyresase
reduced no. of scfa
52
what is aproboitics
a live microcorim that when admistred in an adequete amount has a helab benfit
53
what is a preboitic
a subatn that selecilty utilsed by host microogaim conferring a host benifit
54
what role are carried out by many bacteria
competoin, barrier and reuciotn of inlaotm
55
what roles in the body are carried out by a limmited no. of bacteri
bioconserion diet direction antagoism immune stimulation
56
what is the ratte effect form microboiome
prodution of vitamens
57
why are proboics hard to judge
large no. of thtem they are indivalist
58
what can preboics secte in brain
scfa which rect wiht immuen clls
59
health benfis of preboics
increase insuil senivy, incread barrier funion, reudced inlaoma nd lipids increased stiety, reudced food intake increaed imune boosint , reuicng inflaion and allergic rections increaed claclum absopon
60
exampoe of preboic
b glucan fibr form oats/ barley
61