alzheimers Flashcards

1
Q

sx of alzheimers

A

memory loss
repeating words
not able to learn
poor cordination and motor function
personality changes
inappropriate behavior
hallucinations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

what drugs worsen dementia

A

antiemetics- promethazine
anti histamine - diphenhydramine and doxylamine
anti pscyh- chlorpromazine aripriprazole
barbituates-
benzos
central anticholinergics
peripheral anticholinergics
skeletal muscle relaxants– baclofen
opiods and sedatives

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

screening done by

A

MMSE<24

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

natrual products

A

vit e 2000units
ginko
*bleeding risk with both
vit D

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

drug tx

A

acetylcholinesterase inhibitor
with or without memantine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

steps of therapy

A

dc any harmful drugs
exercise
eat healthy
BG control
activity of brain

start ach inhi
start memantine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

what are some ach i

A

MOA- increase ach by blocking enzyme receptor
donepezil (aricet)
rivastigmine (Exelon)- patch
galantamine

MOA- blocks NMDA receptor inhibits glutamate
memantine (namenda)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

drug interactions with ACHi

A

drugs that cause HR lowering
anticholinergics
caution with NSAIDS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

common ACHi AE

A

nausea- take at night
diarrhea
decreased HR

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

exelon patch

A

apply new patch same time upper/lower back or upper arm
rotate sites (do not use same site upto14 days)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

what are some AE of ACHi

A

N/Diar/ weight loss brady cardia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

whcih are available ODT

A

donepezil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

aricept

A

donepezil

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

namzeric

A

donepezil +memantine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

namendaa

A

memantine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

namenda can be used mono therapy for mod to severe alzheimer

A

true

17
Q

namenda AE

A

dizziness conusion HA