compounding III

Question 1

a compounding record should have

Answer 1

what you did
specific to the compound
staff invoilved with the prep along with
BUD Steps etc

Question 2

make products accordnign to the

Answer 2

master formula

Question 3

comminution

Answer 3

trituration grind into fine pwoder
levigation (levigating agent

Question 4

solutions

Answer 4

syrups- sucrose
elixirs sweet hydroalcholoics
tinctures - plant or aminal extract
spirits alcohol

Question 5

suspension

Answer 5

wetting/levigating agent used to mix solid with liquid

Question 6

emulsion

Answer 6

liquid immix=scible to another liquid

Question 7

how to prepare emulsion

Answer 7

4 oil
2 water
1 gum

Question 8

ficks law

Answer 8

dissolution rate

Question 9

sodium lauryl sulfate

Answer 9

surfactant
for static charge

Question 10

melting point order

Answer 10

highest first to lowest

Question 11

eutectic mixtures

Answer 11

two compounds that when mixed together hav elower melting point
MGO used to keep powder dry

Question 12

lozenge

Answer 12

PEG for soft
sucrose/syrup for harder

Question 13

GEls

Answer 13

PLO
pluronic lecithin organogel for transdermal drug administration

Question 14

ppository

Answer 14

oil- cocoa , theoroma
veg oil cocnut
water- peg, gelatin

Question 15

density factor

Answer 15

B/A-C+B
weight of med per suppository/ weight of black - weight of medicated suppo +medicated suppository

Question 16

non aquas BUD

Answer 16

6 months

Question 17

water containing

Answer 17

14 days

Question 18

water containing topical

Answer 18

30 days at RTP

Question 19

unit dose expiration

Answer 19

6 months or manufaturers exp if earlier than 6 months

Question 20

testing high risk product

Answer 20

tryptic soy agar
fluid thioglycolate
baterial endotoxin test

Question 21

label requirements i

Answer 21

name
strength
volume
BUD
route
storage
aux labels ( high alert, hazardous etc

Question 22

bacterial endotoxin test

Answer 22

limulus amebocyte lysate

Question 23

low risk sterile compounding

Answer 23

1-3 sterile components
<2 entries
48 hours 14 days 45days

Question 24

medium risk sterile compounding

Answer 24

preparing a batch
30 hours 9 days 45 days

Question 25

high risk sterile compounding

Answer 25

non sterile ingredients or equipments
sterile components held outside ISO 5 air for more than 1 hour
24 hours 3 days and 45 days

Question 26

low risk but in an iso 5 or not in a clean room

Answer 26

12 hours 12 hours N/A

Question 27

test to find out the integrity of the filter

Answer 27

bubble point test

Question 28

heat labile csps need to be filtered through

Answer 28

filter needle 0.22mcg

Question 29

single dose container BUDs ampule

Answer 29

discard no bud

Question 30

singel dose container bud inside ISO5 bud

Answer 30

upto 6 hours

Question 31

singel dose container bud outside ISO5

Answer 31

1 hour

Question 32

quality assurance

Answer 32

presonnel training and assessment
environement monitoring
equipment calibration

Question 33

recall

Answer 33

class 1 death
class2 temporary reversible AE
class3 does not cause any health consequences

Question 34

tonicity

Answer 34

solutes that do not cross

Question 35

osmolarity

Answer 35

solute concentration including tonicity