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naplex > constipation and diarrhea\ > Flashcards

constipation and diarrhea\ Flashcards

1
Q

non drug tx for constipation

A

increase fluid intake
limit caffiene and alcohol
food with fiber

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2
Q

drugs for constipation

A

bulk forming drugs
osmotics
stimulants
stool softners
lubricants

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3
Q

bulk forming drugs

A

1st line
pregnancy
MOA absorb water in the intestines soaking up fluid

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4
Q

osmotics

A

peg
milk of mg
glycerin
lactulose
sodium phos enema

large ions
drawing fluid from intestines

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5
Q

stimulants

A

senna,
bisacodyl
used to tx chronic opiod

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6
Q

stoolsoftners are given when

A

docusate
iron suppplement patients

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7
Q

what are some bulk forming drugs

A

Psyllium (metamucil)
Calcium polycarbophil (fibercon)
methylcellulose (citrucel )
Whear dextrin (benefiber)

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8
Q

what are some key points with bulk forming drugs

A

adequate fluids are required
AE- flatulence, abdominal cramping, bloaing

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9
Q

what are some osmotics

A

MGOH (milk of magnesia
polyethylene glycol 3350 (miralax)
Glycerin
lactulose
sodium phosphates(fleet enema)

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10
Q

what are some key points with osmotics

A

electrolyte impbalance
abdominal cramping
MG care with renal
Glycerin used in children

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11
Q

what are some stimulants

A

senna (exlax, senokot)
bisacodyl

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12
Q

stool softners

A

Docusate

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13
Q

other drugs used for constipation

A

chloride channel activator
guanalate cyclase C agonist
peripherally acting mu opiod receptor antagonist (PAMORAs)
serotonin 5HT4 receptor agonist

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14
Q

Lubiprostone

A

Amitiza
Chlorine channel activator
AE- nausea

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15
Q

linaclotider

A

linzess
AE-diarrhea
do not use in pediatric pts

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16
Q

peripherally acting mu opiod receptor antagonists

A

Alvimopan(entereg)
methylnaltrexone (relistor)
Naloxegol (movantik)
AE- risk of MI with longterm use

17
Q

5HT4 receptor agonist

A

prucalopride (motregrity
tegaserod(zelnorm)
AE- suicidal ideation, diarrhea

18
Q

laxative used for whole bowel irrigation

A

colonoscopy
polyethylene glycol(colyte, goLytely, Nulytely
sodium phosphates (osmoprep
Sodium sulphate, potassium sulphate and MG sulphate (suprep bowel prep kit

19
Q

Osmoprep should be avoided in

A

acute phosphate nephropathy
gastric bypass or stapling surgery
BW- nephropathy

20
Q

causes of diarrhea

A

milk -lactose intolerant
IBSD

21
Q

non drug tx

A

fluid and electrolyte replacement
oral rehydration solutions

22
Q

drug tx

A

bismuth salisylate- peptobismol
loperamide
mu receptor agonist

23
Q

anti diarrheals

A

bismuth
loperamide (immodium)
diphenoxylate/atropine (lomotil)

24
Q

antipasmodic

A

dicylomine (bentyl)

25
Q

peripherally acting mu receptor agonist

A

eluxadoline (viberzi) control

26
Q

what are the controlled substances used for diarhhea

A

diphenoxylate/atropine (lomotil)
eluxadoline (viberzi)

27
Q

other meds for diarrhea

A

abx- rifaximin (xifaxan)
serotonin receptor antagonist (alosetron (lotronex)

28
Q

bismuth

A

salisylate allergy
reyes syndrome
black tongue/stool
tinnitis
nausea
risk of bleeding with anticoag/plat

29
Q

loperamide

A

4mg after first loosoe and then 2mg after each loose stool max 8mg/day
constipation
do not use >48 hours

30
Q

which med can cause anticholinergic effects

A

dicyclomine

31
Q

what drugs can cause diarrhea

A

acetylcholinesterase inhibitor donepezil
antacids with MG
ABX
metformin, GLP
colchicine
laxatives
misprostol
mycophenolate
protease inhibitor
quinidine
roflumilast
MTX, irinetican , flurouracil
metochlopramide , cisapride

32
Q

what drugs can cause constipation

A

antacids with Cal aluminum
antidiarrheals
clonidine
colesevelam
anticholinergic
iron
non DHP CCBs
opioids
sucralfate

33
Q

which drug is for short term use for constipation for ileus sx

A

alvimopan (enterag)

naplex (78 decks)

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