compounding II: equipment, stability and excipients Flashcards

1
Q

a graduates capacity should be more than

A

20% of the volume it measures for 100ml = 20ml

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2
Q

what are the balances used in compounding

A

class III or class A balance with MWQ

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3
Q

MWQ is

A

usually accepted rate is 5%
MWQ= Sensitivity requiremetn/Acceptable rate

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4
Q

what type of mortar is used for liquid or suspension or oily and stainy

A

glass

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5
Q

what type of mortar is used for crystals and hard powder

A

wedgwood mortars

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6
Q

what type of mortars are used for blending powders and gummy constituents

A

porecelain mortars

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7
Q

what are capsule sizes

A

000- 5

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8
Q

High quality ingredients are recommended in

A

USO-NF
FCC- food chemicals codex

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9
Q

what are the use of a surfactants what are the types of surfactant

A

used to lower tension so that its easier for two products to mix
- wetting agents
- emulsifiers
- suspending agents
- levigating agents
- foaming agents
- glycols and gels

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10
Q

HLB <10 used for

A

water in oil
L is lipophilic

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11
Q

what are some binders

A

acacia
starch
sucrose
compressible sugar for stability

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12
Q

what are some disintigrating agents

A

alginic acid
cellulose
ploarcillin potassium
starches

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13
Q

lubricants

A

MG stearate

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14
Q

preservatives

A

chlorhexidine
sodium benzoate
sorbic acid
EDTA
thimerosal

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15
Q

buffers

A

acids and hydroxides

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16
Q

excipients to avoid in children

A

alcohol

17
Q

what has PKU

A

aspartame

18
Q

celeac disease pepole should avoid

A

glutan

19
Q

neonates should avoid

A

preservatives

20
Q

sorbitol

A

IBS cannot be used

21
Q

Xylitol can

A

GI upset

22
Q

if not from fda facility which should be used

A

certificate of analysis

23
Q

how to limit oxidative damage

A

temp ph(metalions) light

24
Q

ora plus

A

suspending agent

25
Q

sorbitol

A

plasticiser
sweetner

26
Q

what apart of syringe should not be touched to avoid contamination

A

plunger

27
Q

oil component

A

ointment> cream > lotion

28
Q

usp 795 if a compounding agent comes with no exp date

A

<3 years

29
Q

emulsifiers

A

reduce surface tensions between two liquid