sleep disorder Flashcards

1
Q

insomnia

A

> 3 times weekly for atleast 3 months

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2
Q

non drug

A

sleep hyegine
DC meds that cause insomnia

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3
Q

meds that cause insomnia

A

acetylcholinesterase inhibitors
alcohol
antiretrovirals
aripriprazole
atomoxetine
buprpion
caffine
decongestants
diuretics
fluoxetine if late in the day
steroids
stimulants
varenicline

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4
Q

natural meds

A

melatonin
valerian
chamomile tea

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5
Q

hwat are some sleep hyegines

A

keep room dark comfortable quiet
regular sleep schedule
avoid day naps
reserve bedroom for sleep
establish prebedtime ritual
do not eat heavy meals
do not take caffiene in the afternoon

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6
Q

which drugs help falling and staying asleep

A

eszopiclone
zolpidem

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7
Q

which drugs help falling asleep

A

EZ
ramelteon
zaleplon

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8
Q

which drugs help staying asleep

A

doxepin
suvorexant

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9
Q

what are hypnotics

A

ezopiclone (lunesta)
zolpidem (ambien)
zaleplon (sonata)

all are controlled drugs
preffered over benzos
potential for abuse

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10
Q

orexin receptor antagonist

A

blocks orexin neuropeptide signaling system
lemborexant (dayvigo)
suvorexant (belsomra)

  • somnolence
    do not use in narcolepcy
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11
Q

melatonin receptro agonists

A

MOA- MT1 MT2 receptor agonist
ramelteon (rozerem
tasimelteon

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12
Q

melatonin receptro agonists

A

MOA- MT1 MT2 receptor agonist
ramelteon (rozerem
tasimelteon

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13
Q

tricyclic antidepressant

A

block acetylcholine and histamine receptors
- doxepin silenor
2 week washout with MAO
trazodone and mirtazapine can also be used

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14
Q

benz

A

temazepam
moa- gaba inducer

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15
Q

antihistamine

A

diphenhydramine
doxylamine unisom

  • avoid in BPH and glaucoma
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16
Q

restless leg syndrome

A

dysfunction of dopamine in rain
tx with dopamine agonist and anti convulsants

17
Q

what are some dopamine agonists

A

pramipexole mirapex
ropinoprole requip
rotigotine neupro

18
Q

dopamine agonists AE

A

orthostasis
somnolence

19
Q

gabapentin

A

used for RLS also

20
Q

narcolepsy

A

daytime sleepiness with sudden loss of muscle tone

21
Q

drug tx for narcolepsy

A

stimulants
sodium oxybates

22
Q

what are some stimulants

A

modafinil
armodafinil

23
Q

what are some sodium oxybates

A

derived from GABA
Xyrem C-1
C3 for narcoepsy
restricted through REMS