Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Pharmacology > Anti-inflammatory drugs > Flashcards

Anti-inflammatory drugs Flashcards

(83 cards)

Start Studying
1
Q

what kind of drug is celecoxib

A

cox2 inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

name a cox2 inhibitor

A

celecoxib

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what are the uses of opioids

A

short-term severe pain
long term pain management

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

name some things that can occur due to overdose of aspirin

A

tinnitus
metabolic acidosis +compensatory hyperventilation
Reye’s syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

fluticasone
mometasone
budesonide are what kinds of drugs

A

glucocorticoids used in the treatment of chronic resp inflammation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what stages of pain perception do local anasthetics reduce

A

transmission of pain to the spinal cord

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

name some clinical uses of local anaesthetics

A

local infiltration
regional block
epidural anesthesia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

describe 2 uses of methadone

A

reduce withdrawal symptoms of opioids

eliminate euphoria due to heroin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

how is benzocaine administered

A

topically

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

describe asprin’s effect on cox

A

non-selective
irreversible inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

describe tylenol 1-4

A

Tylenol #1: 300 mg acetaminophen + 8 mg codeine + 15 mg caffeine

Tylenol #2: 300 mg acetaminophen + 15 mg codeine + 15 mg caffeine

Tylenol #3: 300 mg acetaminophen + 30 mg codeine + 15 mg caffeine

Tylenol #4: 300 mg acetaminophen + 60 mg codeine + 15 mg caffeine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

name the main uses of ibuprofen, naproxen and diclofenac

A

anti-inflammatory and analgesic effects (less antipyretic and antiplatelets)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

what kind of drug is aspirin

A

an NSAID

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

what opioid analgesic is used as an antidiarrheal

A

loperamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

how is fentanyl adminsitered

A

transdermally

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

how do local anesthetics work

A

stop axonal conduction by blocking voltage-sensitive Na channels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what are the 3 stages of pain perception

A

detection of pain
transmission of pain to spinal cord
transmission of pain to the brain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

what are some examples of modified cortisol

A

prednisone
betamethasone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

what are some AE at low doses of local anesthetics

A

CNS excitability (seizures)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

how is hydromorphone administered

A

po, sc, im, iv

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

what stage of pain perception do NSAIDs reduce

A

detection of pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

what does cox2 produce

A

harmful prostaglandins

prostaglandins that improve kidney function and reduce thrombosis risk

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

what drug is often combined with tylenol to make tylenol 1-4

A

caffeine and codeine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

name some glucocorticoids used for chronic resp inflammation

A

fluticasone
mometasone
budesonide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
what is an AE of benzocaine
inc levels of methemoglobin that dec oxygen carrying capacity of blood
26
what is the bioavailability of morphine
.35
27
is codeine a stronger or weaker analgesic
weaker
28
what releases histamine
mast cells
29
what is histamine release triggered by
interactions between an allergen and mast cell IgE antibodies
30
prednisone betamethasone are examples of what kind of drug
modified cortisol
31
name a leukotriene antagonist
montelukast
32
what are some adverse effects of antihistamines
sedation xerostomia
33
what is tiotropium
long acting muscarinic antagonist
34
name a glucocorticoids
cortisol
35
what is the drug version of cortisol
hydrocortisone
36
how is methadone adminsited
po
37
what is montelukast used for
treatment of chronic resp infection
38
how is meperidine administered
parentally
39
what stage of pain perception do opioids reduce
transmission of pain to the brain
40
describe the half life of methadone
very long - 1-2 days
41
name two combinations to treat asthma
budesonide and formoterol flutoicasone and salmeterol
42
what things does histamine cause
bronchoconstriction vasodilation inc vascular permeability rhinitis rhinorrhea
43
name some adverse effects of morphine
drowsiness/mental clouding nausea/vomiting constipation miosis hypotension pruritis resp depression tolerance
44
why can cortisol have aldosterone-like effects
because it's structure greatly resembles that of aldosterone
45
what are some clinical uses of prednisone and bethamethasone
suppress immune response resp dieseases, autoimmune diseases, IBD treat dermatological conditions boost fetal lung maturation adjuct to chemo
46
name some AE of other NSAIDs
GI irritation/ulcers renal insufficiency inc NA/h20 retention inc preload inc BP
47
what two bronchodilators are used in the treatment of asthma
salbutamol tiotropium
48
what is different between aspirin and the three other NSAIDs we learned about
the other 3 are reversible inhibitors of cox the other three have less antiplatelet effects
49
how is buprenorphine and naloxone administered
sublingually
50
name 3 NSAIDs besides aspirin
ibuprofen naproxen diclofenac
51
what opioid analgesic has the potential for serotonin syndrome
meperidine
52
name some antihistamines
diphenhydramine desloratadine bilastine dimenhydrinate
53
what is the difference between cortisol and modified cortisol
modified cortisol has less mineralocorticoid effects
54
name some adverse effects of prednisone and bethamethasone
inc infection risk slow wound realing inc plasma glucose inc BP protein catabolism redistribution of adipose tissue osteoporosis mood changes (euphoria) glacoma cataracts
55
why can aspirin exacerbate resp disease
due to inc of leukotrienes
56
gabapentin pregabalin amitriptyline are examples of what type of drugs
analgesics (dont fit into any of the main categories we learned about)
57
what is reyes syndrome
acute encephalopathy with cerebral edema and hepatic steatosis
58
name; 4 things that aspirin does
antiplatelet effects anti-inflammatory antipyretic analgesic
59
why is tylenol preffered over ASA
less toxicity - no reyes syndrome, hypersensitivity, GI or hema effects
60
what anti-histamine is also used to reduce motion sickness
dimenhydrinate
61
why does aspirin cause gastric ulcers
due to dec prostaglandins
62
what does the body release as a long-term response to stress
glucocorticoids
63
how is oxycodone adminstered
po
64
why would a combination of buprenorphine and naloxone be safer than methadone for withdrawl symptoms
less risk of overdose
65
why is meperidine a short term use only
because it's metabolite can be neurotoxic
66
why does aspirin cause inc bleeding time
due to dec thromboxane A2 and less platelet aggregation
67
what drug when combined with tylenol makes percocet
oxycodone
68
name some adverse effects of celecoxib
thrombosis reduced renal function
69
why is buprenophine helpful for antagonizing opioids
its a partial agonist - limits stimulatory effects
70
what drug gets converted to morphine by CYP 2D6
codeine
71
what are some symptoms of aspirin exacerbated resp disease
asthma nasal polyps hypersensitivity
72
how is codeine administered
po
73
name an opioid antagonisst
naloxone
74
what opioid analgesic is used to eliminate the euphoria associated with heroin
methadone
75
diphenhydramine desloratadine bilastine are what kinds of drugs
antihistamines
76
what is the antidote to a tylenol overdose
N-acetylcysteine
77
what is the brand name for the combo of buprenorphine and naloxone
suboxone
78
how do NSAIDs work
inhibit COX enzymes taht produce thromboxane A2 and prostaglandins
79
what occurs due to tylenol overdose
hepatotoxicity caused by metabolites + death
80
name some adverse effects of aspirin
prolonged bleeding GI irritation/ulcers renal insufficency Na/h20 retention ^inc preload inc BP resp disease`
81
name some other analgesics that don't fit into any of the main categories mentioned
gabapentin pregabalin amitriptyline
82
name 2 local anesthetics
benzocaine lidocaine bupivacain
83
name 2 therapeutic effects of antihistamines
moderate anti-inflammatory effect nasal vasoconstriction

Pharmacology (22 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions