Antivirals

Question 0

What are the general signs and symptoms of viruses? (will be on exam)

Answer 0

Headache, fever, cough
NVD
Fatigue, muscular pain

Question 1

What is the method of transmission for viruses?

Answer 1

Coughing, sneezing

Question 2

What are influenza virus vaccine composed of?

Answer 2

Eggs

Question 3

What do you need ask the patient before giving influenza virus vaccine?

Answer 3

If they are allergic to eggs

Question 4

What antiviral medications are given for just Influenza A?

Answer 4

Amantidine (Symmetrel)

Rimantadine (Flumadine)

Question 5

What is needed for Influenza A and B?

Answer 5

Neuraminidase inhibitors

Question 6

What antiviral meds are used against Influenza A and B?

Answer 6

Zanamivir (Relenza)

Oseltamivir (Tamiflu)

Question 7

How does Ostamivir (Tamiflu) work?

Answer 7

Inhibits viral replication if given within 24 hours of symptoms

Question 8

What antiviral contains antibodies and protects 2-3 weeks, repeated?

Answer 8

Gamma Globulin

Question 9

Why Gamma globulin given IM to provide?

Answer 9

Passive immunity

Question 10

Why Gamma globulin given IV?

Answer 10

For immediate immunity

Question 11

What are Topical non-HIV antivirals used to treat?

Answer 11

Herpes simplex virus

Question 12

What is an example of Topical non-HIV antiviral?

Answer 12

Idoxuridine (Herplex Liquifilm)

Question 13

What is the action of Purine Nucleosides?

Answer 13

Interferes with viral DNA synthesis

Effective against various herpes viruses

Question 14

What Purine Nucleosides treats herpes simplex, herpes zoster, varicella-zoster virus, CMV?

Answer 14

Acyclovir (Zovirax)

Question 15

What blood levels need to be watched when giving Purine Nucleosides?

Answer 15

BUN, Creatinine, GFR labs

Question 16

What are the nursing interventions for Acyclovir (Zovirax)?

Answer 16

Administer IV over 60 minutes

Monitor CBC, renal, liver test, urine output, BP, superinfections

Question 17

What do you need to teach patient when giving Acyclovir (Zovirax)?

Answer 17

Increase fluid intake for toxicity

Practice abstinence or use condoms

Question 18

Protozoan disease

Answer 18

Malaria

Question 19

What happens in the tissue phase of malaria?

Answer 19

No symptoms

Question 20

What happens in the erythrocytic phase of malaria?

Answer 20

Fever, chills, sweating, flulike symptoms

Question 21

What are antimalarial drugs?

Answer 21

Hydroxychloroquine (Plaquenil), Quinine (Quinamm), Mefloquine (Lariam)

Question 22

What is Plaquenil also used for?

Answer 22

Lupus

Question 23

When do you treat malaria prophylactically?

Answer 23

When leaving the country

Question 24

What are some important SE of Plaquenil?

Answer 24

GI distress, mental changes, blurred vision, and blood dyscrasias

Question 25

What is the main SE of Quinine?

Answer 25

GI distress and eighth cranial nerve damage

Question 26

What are the nursing interventions with antimalarials?

Answer 26

Kidney and liver function, take with meals, report vision or hearing changes

Question 27

Parasitic worm

Answer 27

Helminth

Question 28

How long do you give an antihelmintic?

Answer 28

1-3 days

Question 29

What is the main SE of an anhelmintic?

Answer 29

GI upset

Question 30

What the nursing interventions with an antihelmintic?

Answer 30

Take after meals, good hygiene, warn against driving

Question 31

What is a SE of prolonged acyclovir use?

Answer 31

Gingival hyperplasia