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Flashcards in Antivirals Deck (32):
0

What is the method of transmission for viruses?

Coughing, sneezing

1

What are the general signs and symptoms of viruses? (will be on exam)

Headache, fever, cough
NVD
Fatigue, muscular pain

2

What are influenza virus vaccine composed of?

Eggs

3

What do you need ask the patient before giving influenza virus vaccine?

If they are allergic to eggs

4

What antiviral medications are given for just Influenza A?

Amantidine (Symmetrel)
Rimantadine (Flumadine)

5

What is needed for Influenza A and B?

Neuraminidase inhibitors

6

What antiviral meds are used against Influenza A and B?

Zanamivir (Relenza)
Oseltamivir (Tamiflu)

7

How does Ostamivir (Tamiflu) work?

Inhibits viral replication if given within 24 hours of symptoms

8

What antiviral contains antibodies and protects 2-3 weeks, repeated?

Gamma Globulin

9

Why Gamma globulin given IM to provide?

Passive immunity

10

Why Gamma globulin given IV?

For immediate immunity

11

What are Topical non-HIV antivirals used to treat?

Herpes simplex virus

12

What is an example of Topical non-HIV antiviral?

Idoxuridine (Herplex Liquifilm)

13

What is the action of Purine Nucleosides?

Interferes with viral DNA synthesis
Effective against various herpes viruses

14

What Purine Nucleosides treats herpes simplex, herpes zoster, varicella-zoster virus, CMV?

Acyclovir (Zovirax)

15

What blood levels need to be watched when giving Purine Nucleosides?

BUN, Creatinine, GFR labs

16

What are the nursing interventions for Acyclovir (Zovirax)?

Administer IV over 60 minutes
Monitor CBC, renal, liver test, urine output, BP, superinfections

17

What do you need to teach patient when giving Acyclovir (Zovirax)?

Increase fluid intake for toxicity
Practice abstinence or use condoms

18

Protozoan disease

Malaria

19

What happens in the tissue phase of malaria?

No symptoms

20

What happens in the erythrocytic phase of malaria?

Fever, chills, sweating, flulike symptoms

21

What are antimalarial drugs?

Hydroxychloroquine (Plaquenil), Quinine (Quinamm), Mefloquine (Lariam)

22

What is Plaquenil also used for?

Lupus

23

When do you treat malaria prophylactically?

When leaving the country

24

What are some important SE of Plaquenil?

GI distress, mental changes, blurred vision, and blood dyscrasias

25

What is the main SE of Quinine?

GI distress and eighth cranial nerve damage

26

What are the nursing interventions with antimalarials?

Kidney and liver function, take with meals, report vision or hearing changes

27

Parasitic worm

Helminth

28

How long do you give an antihelmintic?

1-3 days

29

What is the main SE of an anhelmintic?

GI upset

30

What the nursing interventions with an antihelmintic?

Take after meals, good hygiene, warn against driving

31

What is a SE of prolonged acyclovir use?

Gingival hyperplasia