Infections for Patho Flashcards

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0
Q

Microorganisms normally living in or on body

A

Microflora

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1
Q

Microorganisms are multiplying in or on a host

A

Infection or colonization

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2
Q

What cause disease?

A

Pathogens

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3
Q

Pathogen capable of producing infection when host is weakened

A

Oppurtunistic pathogen

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4
Q

Small modified infectious host proteins

A

Prions

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5
Q

Manner of replication of prions

A

Not clearly known or understood

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6
Q

Where do bacteria like to grow?

A

Warm moist places

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7
Q

What stage is active replication without recognizable symptoms in host?

A

Incubation

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8
Q

Stage with initial appearance of symptoms most commonly malaise

A

Prodromal

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9
Q

When are you most highly infectious?

A

Prodromal stage

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10
Q

What stage is the maximum impact of infectious process with rapid proliferation and dissemination of pathogen

A

Acute

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11
Q

Stage where there is containment if the infection, elimination of pathogen, repair of danger tissue, and resolution of symptoms

A

Convalescent

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12
Q

What stage is total elimination of pathogen and no S/S of disease?

A

Resolution

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13
Q

When are you not infectious anymore?

A

Resolution stage

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14
Q

-itis

A

Inflammation

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15
Q

-emia

A

In the blood

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16
Q

Bacterial toxins in the blood

A

Sepsis or septicemia

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17
Q

Make an infection more likely to cause disease

A

Virulence factor

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18
Q

Exotoxins

A

Outside

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19
Q

Endotoxins

A

Inside

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20
Q

Help infective organism stick to body

A

Adhesion factor

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21
Q

Help keep immune system from killing infective agent

A

Evasive factor

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22
Q

After exposure to an infectious agent the body produces antibodies

A

Serology

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23
Q

Antibody that rises during the acute phase then falls

A

IgM

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24
Antibody that remains elevated after the acute phase
IgG
25
What is the genetic material of viruses?
DNA or RNA but not both
26
What do viruses need to replicate and why?
Host cell because they have no metabolic capability
27
What happens when a host cell is "transformed"?
It carries the virus
28
What is a virus responsive to that makes it become active?
Stress or hormonal changes
29
What are the effects of viruses?
Protein synthesis stops, enzymes kills cells, host cells fuse, secondary bacterial infections
30
Where is HSV type 1 located?
Above the belt
31
Where is HSV type 2 located?
Below the belt
32
Inflammation of the dorsal root ganglia
Shingles
33
What are the 3 ways antivirals work?
Interfere with nucleic acid synthesis, do not allow binding of cells to virus, and stimulate the body's immune system
34
Used to treat HSV, HSV 2, and varicella zoster
Acyclovir
35
How is acyclovir most commonly administered?
Topical
36
Does acyclovir cure the illnesses?
No it decreases the length of them
37
What is a risk of giving acyclovir with AZT?
Neurotoxicity
38
Used for treatment of HIV
Zidovudine
39
How does zidovudine work?
Inhibits reverse transcriptase for replication
40
What is an important SE of zidovudine?
Bone marrow suppression
41
Drugs that reduce the duration of influenza A and B
Tamiflu and Relenza
42
When should you start Tamiflu and Relenza?
Within 2 days of first symptoms
43
When should you not give antivirals?
If patient has herpes zoster or is immunosuppressed
44
One celled organisms with no true nucleus
Bacteria
45
Released when the bacterial cell wall decomposes
Endotoxins
46
Released during cell growth
Exotoxins
47
Why are endotoxins pyrogenic?
Due to lysis of bacteria
48
Bacteria requires oxygen
Aerobic
49
Bacteria doesn't require oxygen
Anaerobic
50
Bacteria in blood
Septicemia
51
How is TB transmitted?
Droplet
52
What is the usual protocol for TB treatments?
Drug susceptibility tests, start 4-drug regimen, adjust after susceptibility test results
53
What is a must in TB treatments?
Patient compliance
54
How long is TB treatment?
6 months
55
What TB drug inhibits protein synthesis?
Rifampin
56
What TB drug inhibits cell wall synthesis?
Isoniazid
57
When giving isoniazid what is it important to monitor?
Liver
58
What is a SE of rifampin?
Bodily secretions turn red-orange/brown
59
When do you take TB meds?
With meals
60
Infection caused by fungus
Mycosis
61
Mycotic infection that affects lungs
Blastomycosis
62
What are examples of mycotic cutaneous infections?
Candidias, dermatophytes, and tinea
63
Med for systemic mycoses
Amphotericin B
64
What can amphotericin B do to potassium levels?
Decrease them
65
What drug do you use caution with when giving amphotericin B?
Digoxin
66
What is a bad side effect of amphotericin B?
Nephrotoxic
67
What other drug can you give besides amphotericin B and why would you?
Fluconazole because it has less SE
68
What can fluconazole increase?
Anticoagulant effects and phenytoin levels
69
How do fungi reproduce?
Division
70
What are the two classifications of fungi?
Yeasts and molds
71
Single celled or multi celled organisms
Parasites