Anxiety and Depression Shit Flashcards Preview

Undeleted > Anxiety and Depression Shit > Flashcards

Flashcards in Anxiety and Depression Shit Deck (22):
1

"emotional brain"

limbic system: appraisal, response, reversal of arousal

2

GABA dysfunction in anxiety

GABA calms.

GABA release from post-synaptic sites = anxiety

3

5HT dysfunction in anxiety

5HT tends to be excitatory (can be either).
increased 5HT, decreased 5HT1

low levels = serotonin reuptake inhibitors to allow more serotonin to be available

4

NE dysfunction in anxiety

malfunctioning system = decreased arousal

increased HR, O2 use, midbrain activity = NE release

increased NE = excitatory = anxiety

5

panic disorder is

recurrent, unexpected panic attacks
at least 1 of the attacks is followed by:
-- persistent worry about more attacks
-- worry about implications/consequences

less of a stressor triggers NE

50% before age 24, 2x women
comorbidity with depression, substance abuse
30% develop agoraphobia

6

#1 medication for panic attacks & why

tricyclic antidepressants, because of effect on NE
(or SSRI ok too)

beta blockers not helpful for panic attacks

7

#1 non-pharm treatment for panic attacks

SAFETY. CBT.

8

specific phobia is

x2 women, high proportion of men seek help
typically young when manifested, rarely > 25
comorbid with depression (25%), substance abuse

9

phobia receptor

primarily GABA

10

social anxiety disorder (social phobia)

is a specific phobia
beta blockers help

11

phobia pharm

benzos, beta blockers, SSRIs

12

ocd categories

obsessive compulsive disorder
body dysmorphic disorder (somatic symptom disorder)
hoarding
hair pulling, skin picking , etc

NOT same as obsessive compulsive PERSONALITY disorder

13

ocd is

difficulty planning because of poor thought filter; compulsions used to deal with anxiety

obsessions: thoughts, compulsions: behavior

primarily 5HT, basal ganglia, cingulum (limbic), smaller caudate size

14

ocd non-pharm treatment

behavioral therapy

15

ocd pharm treatment

luvox (fluvoxamine) + other SSRIs
TCAs

16

generalized anxiety disorder

"chronic" anxiety

likely 5HT

a. Excessive anxiety (worry) for at least six months about a number of events or activities
b. The persons finds it difficult to control the worry c. Three or more of the following symptoms:
(1) Restlessness/feeling keyed up-on edge
(2) Easily fatigued
(3) Difficulty concentrating - "mind going blank"
(4) Irritability
(5) Muscle tension
(6) Sleep disturbance

17

gad non-pharm

EXTREMELY effective
CBT, cognitive reframing, stress management, lifestyle mod, support groups

18

gad pharm

buspar, valium, TCA, SSRI

19

too little 5HT

depression

20

slightly elevated 5HT

anxiety

21

too much 5HT

serotonin syndrome, cardiac shit

22

serotonin syndrome s/s

fever, tremor, coma, seizures, death

Decks in Undeleted Class (79):