Anxiolytic and Sedatives Flashcards Preview

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Flashcards in Anxiolytic and Sedatives Deck (19):
1

How does alcohol change the affect of anxiolytics

It potentiates their affect

2

How do benzos and barbiturates compare to GABA MOA

They have receptors adjacent to GABA receptors, which changes the configuration of the GABA receptor

3

what happens in a barbiturate overdose

coma (death from aspiration of vomitus), respiratory depression

4

What is an example of an ulta-short acting barbiturate

Thiopental/ Pentothal

5

What is an example of a short acting barbiturate

Pentobarbital/ Nembutal

6

What is an example of a medium-acting barbiturate

Butalbital/ Fiorinal

7

What is an example of a long-acting barbiturate

Phenobarbital/ Luminal

8

What are the indications of phenobarbital

anti-seizure, sedative

9

What type of drug is Midazolam (Versed)

short-acting benzodiazapene

10

What are the indications of diazepam (Valium)

Anxiolytic, sedative, muscle relaxant and seizure control (breakthrough seizure)

11

What drug type is zolpidem (Ambien)

short-acting non-benzodiazepine hypnotic

12

What is the MOA of zolpidem (ambien)

potentiates GABA by binding to GABAA receptors at the same location as benzodiazepines

13

What are risks of taking zolpidem (ambien)

somnabulance with no memory of it (even driving). Take Ambien-CR (controlled release) to help this problem

14

What drug class is Eszopiclone (Lunesta)

benzodiazepine-like hypnotic

15

What are side effects of Eszopiclone (Lunesta)

Impaired mentation prior to sedation

16

What drug class is Ramelteon

melatonin receptor agonist

17

What is a complication of withdrawal from a benzodiazapine or barbiturate

Rapid withdrawal can cause death

18

What are Benzo withdrawal symptoms

seizure, hallucinations, anxiety, panic attacks, etc can last years

19

What is flumazenil (Romazicon)

IV drug used to bring people back from a benzo OD