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AssesUw1 Flashcards

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1
Q

what is Mosaicism

A

X diff cell lines

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2
Q

what is germline mosaicism

A

involves oocytes/spermatocytes (CHILD HAS IT but parents do NOT

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3
Q

what artery is affected in posterior tibia dislocation

A

POPLITEAL(also primary BS for calf/foot)

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4
Q

postpardum endometritis is MC in what structure

A

UTERUS

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5
Q

Sublimation

A

when u channel unacceptable thoughts/impulses to socially acceptable behavior

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6
Q

what ions does salivary gland has low/high of

A

LOW=Na+ Cl-

HIGH=K+

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7
Q

timeline for acute stress disorder

A

> 3days<1mo

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8
Q

ARR

A

control rate - treatment rate

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9
Q

what is the SERUM K+/NA in DKA

A

High=K+

Low=Na+

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10
Q

LH, FSH, TESTO in AIS

A

46XY but female PHENOTYPE HIGH=LH, TESTO

LOW=FSH

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11
Q

how does Nitrates effect HR/LVEDV

A

INCREASE HR, DECREASE LVEDV

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12
Q

CF has what ions lvl in sweat

A

INCREASE Na+/Cl

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13
Q

CF has what ions lvl in respiratory

A

secretions are LOW in Na+/Cl

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14
Q

problem w/ Pseudohypoparathyroidism

A

end organ resistance to PTH

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15
Q

lab values/presentation of pseudohypoPTH

A

Ca+ LOW
PTH, PO4= HIGH
short stature/fingers round face

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16
Q

what’s an AD form of pseudohypoPTH (MOM)

A

Albright Hereditary Osteodystrophy(GNAS1) codes for a of Gs protein(mediates effects of PTH)

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17
Q

DNA LOOPS are only form after what

A

RNA splicing has occured (removal of introns)

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18
Q

ELISA is used to do what

A

specific antibodies(IgG peroxidase)

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19
Q

what’s a common cause of bacteria multi drug resistance

A

EFFLUX PUMPS

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20
Q

Bruton is caused by what defect

A

BTK gene on X-chromo

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21
Q

what does proteins destined for the RER posses & if they don’t hv it where does it accumulate

A

they hv HYDROPHOBIC N-Terminal peptide signal sequence. IF they DON’T hv they accumulate in the CYTOSOL

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22
Q

what can cause howel jolly bodies

A

asplenia(surgically removal)/SS

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23
Q

what cell is effected if you have a low Testo in seminiferous/epididymis

A

SERTOLI

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24
Q

what receptor does the liver/glucagon EPI use for gluconeogeesis, glycogenolysis

A

Gs

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25
what ABG does PE cause
RESPIRATORY ALKALOSIS
26
Hypoglycemia/LOW KETONES after fasting suggest what
impaired beta oxidation Medium chain Acyl-Coa dehydrogenase def.
27
chromogranin/synaptophysin is a marker for what tumor
Carcinoid(5HT) GI/LUNG
28
what DM drugs use SGLT-4
PIOGLITAZONE(PPAR-Y)
29
MOA LACTULOSE
acidifies GI convert NH3 to NH4 so it can be EXcreted
30
what second mesenger/receptor is stimulated to cause BRONCHODIALATION
B2/Increase cAMP
31
you have a decrease in what in OSTEOMALACIA(VIT D)
mineralazation of OSTEOID
32
what are the mjr risk factors for Peripheral Arterial Disease
DM, Smoking, HTN, hyperchol.
33
presentation of peripheral arteriosclerosis
pts have pain w/leg elevation prefer to sleep in a chair
34
what does germline of a pt that has a family of Li-fraumen shows
INACTIVATING(p53 should be activated) mutation affecting 1 allele
35
what are the muscles L.reccurent laryngeal nerve provide innervation to what muscles
Post./Lat CRICOARYTENOID Oblique/Tranverse ARYTENOID THYROARYTENOID
36
Hoarseness due to aortic arch aneurysm is due to what nerve
Left Recurrent Laryngeal
37
what nerve does the cricothyroid
External Laryngeal(VAGUS)
38
ALL DNA virus replicate where EXCEPT for
NUCLEUS except for POX
39
RNA viruses replicate where EXCEPT for
CYTOPLASM except for Retro(HIV), Orthomyxo
40
what's the level of O2 in SVC
LOW
41
what causes ACHALASIA
infla/degeneration of neurons in ESO wall
42
PTS w/Broca stroke can present w/
expressive motor aphasia/ slow speech w/agrammatism. but understand spoken language/follow commands
43
what has unmyelinated nerve fibers
postganglionic autonomic nervous system, afferent neurons (heat sensation/slow onset dull burning/visceral pain
44
what size are unmyelinated fibers/are they slow or fast
sml diameter/slow
45
what does Pacinian corpusles mediate
touch/vibratory sensation
46
what MHCII component that is digested by macro during APC
INVARIANT CHAIN
47
Beta-2 microglobulin is used by what MHC
MHCI
48
PAS+ is ass w/ what diz
Whipple
49
MOA phenyleprine
a1>a2 agonist
50
what causes a dilation in the spermatic pampiniform plexus that enlarges w/standing & regress w/lying down
VARICOCELE
51
Long term Leuprolide use causes
DECREASE TESTO SYNTHESIS
52
what are the cardiac problems w/ DiGeorge
Truncus arteriosus, TOF, interrupted aortic arch
53
what is transformation
bacteria tk up naked DNA from environment (Haemophilus, strep, bacilus, Neisseria)
54
what is the SERUM for Nephro DM osmolality, ADH, NA+
SERUM=HIGH | URINE OSMOLALITY is LOW
55
Ehtylene glycol can cause what type of stones
Ca+ oxalate(dumbell/envelope) | ANION GAP ACIDOCIS
56
what structure is mostly effected in Acute RHINOSINUSITIS
Maxillary(middle nasal meatus)
57
what leads to the eustachian tube from the middle ear/ obstruction can cause what
NASOPHARYNX/OTITIS MEDIA
58
MCA causes what type of eye defect
H.H
59
which Band lenghtens during muscle relaxation/shortens during contraction
the I band ( the dark line before the end)
60
where are the thick filaments located
in the A band(lighter one)
61
what medication can you give to help pass a stone
Tamsulosin(a-antagonist) Nifedipine(ca+blkr)
62
where do stones mostly get stuck
VESICOURECTAL(narrowest)

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