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AssesUw1 Flashcards

1
Q

what is Mosaicism

A

X diff cell lines

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2
Q

what is germline mosaicism

A

involves oocytes/spermatocytes (CHILD HAS IT but parents do NOT

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3
Q

what artery is affected in posterior tibia dislocation

A

POPLITEAL(also primary BS for calf/foot)

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4
Q

postpardum endometritis is MC in what structure

A

UTERUS

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5
Q

Sublimation

A

when u channel unacceptable thoughts/impulses to socially acceptable behavior

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6
Q

what ions does salivary gland has low/high of

A

LOW=Na+ Cl-

HIGH=K+

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7
Q

timeline for acute stress disorder

A

> 3days<1mo

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8
Q

ARR

A

control rate - treatment rate

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9
Q

what is the SERUM K+/NA in DKA

A

High=K+

Low=Na+

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10
Q

LH, FSH, TESTO in AIS

A

46XY but female PHENOTYPE HIGH=LH, TESTO

LOW=FSH

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11
Q

how does Nitrates effect HR/LVEDV

A

INCREASE HR, DECREASE LVEDV

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12
Q

CF has what ions lvl in sweat

A

INCREASE Na+/Cl

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13
Q

CF has what ions lvl in respiratory

A

secretions are LOW in Na+/Cl

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14
Q

problem w/ Pseudohypoparathyroidism

A

end organ resistance to PTH

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15
Q

lab values/presentation of pseudohypoPTH

A

Ca+ LOW
PTH, PO4= HIGH
short stature/fingers round face

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16
Q

what’s an AD form of pseudohypoPTH (MOM)

A

Albright Hereditary Osteodystrophy(GNAS1) codes for a of Gs protein(mediates effects of PTH)

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17
Q

DNA LOOPS are only form after what

A

RNA splicing has occured (removal of introns)

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18
Q

ELISA is used to do what

A

specific antibodies(IgG peroxidase)

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19
Q

what’s a common cause of bacteria multi drug resistance

A

EFFLUX PUMPS

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20
Q

Bruton is caused by what defect

A

BTK gene on X-chromo

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21
Q

what does proteins destined for the RER posses & if they don’t hv it where does it accumulate

A

they hv HYDROPHOBIC N-Terminal peptide signal sequence. IF they DON’T hv they accumulate in the CYTOSOL

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22
Q

what can cause howel jolly bodies

A

asplenia(surgically removal)/SS

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23
Q

what cell is effected if you have a low Testo in seminiferous/epididymis

A

SERTOLI

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24
Q

what receptor does the liver/glucagon EPI use for gluconeogeesis, glycogenolysis

A

Gs

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25
Q

what ABG does PE cause

A

RESPIRATORY ALKALOSIS

26
Q

Hypoglycemia/LOW KETONES after fasting suggest what

A

impaired beta oxidation Medium chain Acyl-Coa dehydrogenase def.

27
Q

chromogranin/synaptophysin is a marker for what tumor

A

Carcinoid(5HT) GI/LUNG

28
Q

what DM drugs use SGLT-4

A

PIOGLITAZONE(PPAR-Y)

29
Q

MOA LACTULOSE

A

acidifies GI convert NH3 to NH4 so it can be EXcreted

30
Q

what second mesenger/receptor is stimulated to cause BRONCHODIALATION

A

B2/Increase cAMP

31
Q

you have a decrease in what in OSTEOMALACIA(VIT D)

A

mineralazation of OSTEOID

32
Q

what are the mjr risk factors for Peripheral Arterial Disease

A

DM, Smoking, HTN, hyperchol.

33
Q

presentation of peripheral arteriosclerosis

A

pts have pain w/leg elevation prefer to sleep in a chair

34
Q

what does germline of a pt that has a family of Li-fraumen shows

A

INACTIVATING(p53 should be activated) mutation affecting 1 allele

35
Q

what are the muscles L.reccurent laryngeal nerve provide innervation to what muscles

A

Post./Lat CRICOARYTENOID
Oblique/Tranverse ARYTENOID
THYROARYTENOID

36
Q

Hoarseness due to aortic arch aneurysm is due to what nerve

A

Left Recurrent Laryngeal

37
Q

what nerve does the cricothyroid

A

External Laryngeal(VAGUS)

38
Q

ALL DNA virus replicate where EXCEPT for

A

NUCLEUS except for POX

39
Q

RNA viruses replicate where EXCEPT for

A

CYTOPLASM except for Retro(HIV), Orthomyxo

40
Q

what’s the level of O2 in SVC

A

LOW

41
Q

what causes ACHALASIA

A

infla/degeneration of neurons in ESO wall

42
Q

PTS w/Broca stroke can present w/

A

expressive motor aphasia/ slow speech w/agrammatism. but understand spoken language/follow commands

43
Q

what has unmyelinated nerve fibers

A

postganglionic autonomic nervous system, afferent neurons (heat sensation/slow onset dull burning/visceral pain

44
Q

what size are unmyelinated fibers/are they slow or fast

A

sml diameter/slow

45
Q

what does Pacinian corpusles mediate

A

touch/vibratory sensation

46
Q

what MHCII component that is digested by macro during APC

A

INVARIANT CHAIN

47
Q

Beta-2 microglobulin is used by what MHC

A

MHCI

48
Q

PAS+ is ass w/ what diz

A

Whipple

49
Q

MOA phenyleprine

A

a1>a2 agonist

50
Q

what causes a dilation in the spermatic pampiniform plexus that enlarges w/standing & regress w/lying down

A

VARICOCELE

51
Q

Long term Leuprolide use causes

A

DECREASE TESTO SYNTHESIS

52
Q

what are the cardiac problems w/ DiGeorge

A

Truncus arteriosus, TOF, interrupted aortic arch

53
Q

what is transformation

A

bacteria tk up naked DNA from environment (Haemophilus, strep, bacilus, Neisseria)

54
Q

what is the SERUM for Nephro DM osmolality, ADH, NA+

A

SERUM=HIGH

URINE OSMOLALITY is LOW

55
Q

Ehtylene glycol can cause what type of stones

A

Ca+ oxalate(dumbell/envelope)

ANION GAP ACIDOCIS

56
Q

what structure is mostly effected in Acute RHINOSINUSITIS

A

Maxillary(middle nasal meatus)

57
Q

what leads to the eustachian tube from the middle ear/ obstruction can cause what

A

NASOPHARYNX/OTITIS MEDIA

58
Q

MCA causes what type of eye defect

A

H.H

59
Q

which Band lenghtens during muscle relaxation/shortens during contraction

A

the I band ( the dark line before the end)

60
Q

where are the thick filaments located

A

in the A band(lighter one)

61
Q

what medication can you give to help pass a stone

A

Tamsulosin(a-antagonist) Nifedipine(ca+blkr)

62
Q

where do stones mostly get stuck

A

VESICOURECTAL(narrowest)

wrong (26 decks)

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