wrong/ua Flashcards

1
Q

when u hv an increase in TSH, T3,T4 in a kid what’s the problem

A

they could be resistance to thyroid hormone cuz of inherited mutation in the B receptor(decreases thyroid hormone sensitivity.)

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2
Q

what’s a BARR BOdy and where is it found

A

it’s a DEACTIVATED X chromosome. periphery of the nucleus

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3
Q

what’s association

A

X anomalies w/out a known unifying cause that occur 2gether(VACTERL) Vertebral defects, Anal atresia, Cardiac defects, TE fistula, renallimb abnormalities.

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4
Q

what’s an example of field defect

A

Holopro(tri 13)

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5
Q

where does squamous cell carcinoma of head and neck usually spread

A

ant. cervical(jugular lymph nodes)

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6
Q

what are the 4 cancers that like to spread thru blood

A

follicular carcinoma, renal cell, hepato, choriocarcinoma

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7
Q

what do you expect to be elevated in hyperlipoproteinemia(ApoE3-4)

A

chylomicron, VLDL

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8
Q

what can an infant w/ hydrocephalus develop

A

Macrocephaly, poor feeding, Muscle hypertonicity/hyperreflexia(stretching of periventricular puramidal tracts)

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9
Q

mRNA(micro) can cause what

A

translation repression

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10
Q

What does MRATT stand for

A

Migration, Rolling, Adhesion, Tight adhesion, Transmigration

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11
Q

where will you find P-E selectin

A

R u going to PE

Rolling (P-E selectin)

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12
Q

What CAM would you find in transmigration/FX

A

PECAM-1(helps neutrophils sqz btwn the ENDOTHELIAL cells

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13
Q

where will you find ICAM-1

A

ADHESION(LAD1 def CD8)

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14
Q

what are the risk factors for placenta abruptio

A

HTN, Abdominal trauma cocaine

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15
Q

what is placentae abruptio

A

premature placental separation from uterus (PAINFUL)

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16
Q

what is placentae previa

A

PAINLESS placental implantation over internal cervical OS

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17
Q

which AA is a precursor for 5HT

A

TRYPTOPHAN

18
Q

Tyrosine is a precursor for what neurotransmitters

A

Dopa, NE, Epi Hormones(Thyroxine, Melanin)

19
Q

MOA of Cyproheptadine

A

1st generation anti-histamine (can be given for 5ht syndrome that does NOT respond to supportive measures.

20
Q

what cholesterol medication increase the risk of gallstones /how

A

Cholestyramine by decreasing enteroheptic recirculation of bile acids

21
Q

what’s the DOC for essential tremor(improves w/alcohol)

A

PROPRANOLOL (can causes bronchospasm in COPD/asthma pts)

22
Q

what’s the SV, HR, PVR in propranolol

A
DECREASE= HR, SV
INCREASE= PVR
23
Q

describe RCC

A

clear cytoplasm due to accumulation of lipids/carbs

24
Q

describe Howell-Jolly bodies/what diz found?

A

nuclear remnants in erythrocytes. (sml basophilic spots) Found in Sickle, Hyposplenia, aspleenia.

25
Q

diff btwn Howell, & Heinz bodies

A

Heinz contain iron howell does NOT! that’s y it looks like a blue dot on smear.

26
Q

Leydig contain what type of crystal

A
REINke crystals(eosinophilic)
Ley in the REIN
27
Q

what’s the homologous of Leydig cells in a female

A

Theca Interna(secretes Testosterone)

28
Q

what nerve is effected when you hv to accomodate by titlting your head

A

IV

29
Q

what is the MCC of ATN

A

GENTAMICIN

30
Q

what’s the imp factor for lipohyalinosis

A

CHRONIC HTN

31
Q

what can Amyloid angiopathy cause

A

Cortical Intracerebral hemorrhage in elderly pts w/out trauma, htn

32
Q

what type of melanoma are African/Asian hv an increase for

A

ACRAL LENTIGINOUS

33
Q

what type of melanoma are Caucaisians hv an increase for

A

Lentigo Maligna

34
Q

fenolDopam MOA/TRT/RECEPTOR

A

D1/HTN emergency/GS protein increase cAMP

35
Q

which virus does the rash appears after few days of high fever

A

HHV-6/7 Roseola

36
Q

What;s the difference in the ulcer in HPV VS Syphillis in HIV pts

A

HPV pts ulcer gradually enlarge vs syphillis it heals w/3-6wks

37
Q

a basophilic crescent shape nuclei & pericellular halos w/in macro is what fungus

A

Histoplasma(bird droppings)

38
Q

where would you see EffaceMent foot process in Minimal change

A

EM

39
Q

what would it show on LM for minimal change

A

normaL gloMeruli

40
Q

MOA empaGLiflozin/SE

A

inhib SGLT2 which increases urinary glucose. UTI(vaginal CANDIASIS)

41
Q

where can macro be found in the lymph node

A

MEDULLARY SINUS