wrong/ua

Question 1

when u hv an increase in TSH, T3,T4 in a kid what’s the problem

Answer 1

they could be resistance to thyroid hormone cuz of inherited mutation in the B receptor(decreases thyroid hormone sensitivity.)

Question 2

what’s a BARR BOdy and where is it found

Answer 2

it’s a DEACTIVATED X chromosome. periphery of the nucleus

Question 3

what’s association

Answer 3

X anomalies w/out a known unifying cause that occur 2gether(VACTERL) Vertebral defects, Anal atresia, Cardiac defects, TE fistula, renallimb abnormalities.

Question 4

what’s an example of field defect

Answer 4

Holopro(tri 13)

Question 5

where does squamous cell carcinoma of head and neck usually spread

Answer 5

ant. cervical(jugular lymph nodes)

Question 6

what are the 4 cancers that like to spread thru blood

Answer 6

follicular carcinoma, renal cell, hepato, choriocarcinoma

Question 7

what do you expect to be elevated in hyperlipoproteinemia(ApoE3-4)

Answer 7

chylomicron, VLDL

Question 8

what can an infant w/ hydrocephalus develop

Answer 8

Macrocephaly, poor feeding, Muscle hypertonicity/hyperreflexia(stretching of periventricular puramidal tracts)

Question 9

mRNA(micro) can cause what

Answer 9

translation repression

Question 10

What does MRATT stand for

Answer 10

Migration, Rolling, Adhesion, Tight adhesion, Transmigration

Question 11

where will you find P-E selectin

Answer 11

R u going to PE

Rolling (P-E selectin)

Question 12

What CAM would you find in transmigration/FX

Answer 12

PECAM-1(helps neutrophils sqz btwn the ENDOTHELIAL cells

Question 13

where will you find ICAM-1

Answer 13

ADHESION(LAD1 def CD8)

Question 14

what are the risk factors for placenta abruptio

Answer 14

HTN, Abdominal trauma cocaine

Question 15

what is placentae abruptio

Answer 15

premature placental separation from uterus (PAINFUL)

Question 16

what is placentae previa

Answer 16

PAINLESS placental implantation over internal cervical OS

Question 17

which AA is a precursor for 5HT

Answer 17

TRYPTOPHAN

Question 18

Tyrosine is a precursor for what neurotransmitters

Answer 18

Dopa, NE, Epi Hormones(Thyroxine, Melanin)

Question 19

MOA of Cyproheptadine

Answer 19

1st generation anti-histamine (can be given for 5ht syndrome that does NOT respond to supportive measures.

Question 20

what cholesterol medication increase the risk of gallstones /how

Answer 20

Cholestyramine by decreasing enteroheptic recirculation of bile acids

Question 21

what’s the DOC for essential tremor(improves w/alcohol)

Answer 21

PROPRANOLOL (can causes bronchospasm in COPD/asthma pts)

Question 22

what’s the SV, HR, PVR in propranolol

Answer 22

DECREASE= HR, SV
INCREASE= PVR

Question 23

describe RCC

Answer 23

clear cytoplasm due to accumulation of lipids/carbs

Question 24

describe Howell-Jolly bodies/what diz found?

Answer 24

nuclear remnants in erythrocytes. (sml basophilic spots) Found in Sickle, Hyposplenia, aspleenia.

Question 25

diff btwn Howell, & Heinz bodies

Answer 25

Heinz contain iron howell does NOT! that's y it looks like a blue dot on smear.

Question 26

Leydig contain what type of crystal

Answer 26

``` REINke crystals(eosinophilic) Ley in the REIN ```

Question 27

what's the homologous of Leydig cells in a female

Answer 27

Theca Interna(secretes Testosterone)

Question 28

what nerve is effected when you hv to accomodate by titlting your head

Answer 28

IV

Question 29

what is the MCC of ATN

Answer 29

GENTAMICIN

Question 30

what's the imp factor for lipohyalinosis

Answer 30

CHRONIC HTN

Question 31

what can Amyloid angiopathy cause

Answer 31

Cortical Intracerebral hemorrhage in elderly pts w/out trauma, htn

Question 32

what type of melanoma are African/Asian hv an increase for

Answer 32

ACRAL LENTIGINOUS

Question 33

what type of melanoma are Caucaisians hv an increase for

Answer 33

Lentigo Maligna

Question 34

fenolDopam MOA/TRT/RECEPTOR

Answer 34

D1/HTN emergency/GS protein increase cAMP

Question 35

which virus does the rash appears after few days of high fever

Answer 35

HHV-6/7 Roseola

Question 36

What;s the difference in the ulcer in HPV VS Syphillis in HIV pts

Answer 36

HPV pts ulcer gradually enlarge vs syphillis it heals w/3-6wks

Question 37

a basophilic crescent shape nuclei & pericellular halos w/in macro is what fungus

Answer 37

Histoplasma(bird droppings)

Question 38

where would you see EffaceMent foot process in Minimal change

Answer 38

EM

Question 39

what would it show on LM for minimal change

Answer 39

normaL gloMeruli

Question 40

MOA empaGLiflozin/SE

Answer 40

inhib SGLT2 which increases urinary glucose. UTI(vaginal CANDIASIS)

Question 41

where can macro be found in the lymph node

Answer 41

MEDULLARY SINUS