uworld wrong1 Flashcards

1
Q

what Valve problem and cause can be present after an MI and goes away after treatment

A

MR/due to papilary muscle dysfxn

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2
Q

what heart sound preced S1

A

S4

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3
Q

S4 heart sound is best heard in what position

A

putting the pt lying on there lft side(lft lat. decubitus)

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4
Q

Verapamil MOA

A

Nondi-(heart) slows spontaneous depo( HTN, Afib, angina)

SE; prolactinoma, AV blk, bradycardia, constipation

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5
Q

dystrophic calcification is a hallmark of what

A

cell injury/death(necrosis)

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6
Q

what determines prognosis of TOF

A

Pulmonary stenosis(RV outflow obstruction)

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7
Q

what are the mjr risk for AAA

A

> 65, SMOKING, Male

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8
Q

what causes the continuous murmur in Coarctation of aorta

A

increased blood flow thru collateral blood vessels(internal thoracic art)

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9
Q

Dialated cardiomyopathy is what type of hypertrohy

A

ECCENTRIC(increase vol)

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10
Q

what are chlohexidine(causes leakage of cell membrane disruption) efective against

A

enveloped viruses, bacteria & fungi. NOT effective against nonenveloped icosahedral viruses(hep A picornavirus)

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11
Q

what are sodium hypochlorite & chlorine DIOXIDE effective against

A

naked viruses, spores, protozoa, bacteria they DENATURE PROTEINS

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12
Q

Histo of coagulative necrosis

A

Pale no nuclei also look for wedge shape in organ

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13
Q

fibrinoid necrosis ouccurs in what

A

Vasculitis/malignant HTN

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14
Q

what’s part of the intrinsic ptwy for apoptosis

A

mitochondria, cytochrome C, BCL2

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15
Q

by what ptwy does negative selection induce apoptosis

A

FAS ligand (CD95) extrinsic

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16
Q

melanosomes purpose

A

synthesis/storage of melanin

17
Q

what’s the mechanism behind partial albinism in chediak Higashi

A

due to abnormal intracellular transport of melanosomes cuz of mutation in the LYST

18
Q

Hyperchylomicronemia(I) risk of developing what?

A

def=Apo CII/LPL

pancreatitis, eruptive xanthoma, hepatosplenomegaly.

19
Q

what nerve can be effected in Prostectomy causing erectile DFX

A

cavernous nerve(originate from Inf. hypogastric plexus)

20
Q

In androgen Insensitivity Syndrome what are there presentation

A
Karyotipically male(46XY)
phenotypically=FEMALE blind vaginal pouch
21
Q

what would differentiate Insulinoma VS sulfonylureas

A

Insulin secretagogues is ABSENT in INSULINOMA but present in Sulfonylurea

22
Q

Cyclosporine causes what effect in the mouth

A

GINGIVAL HYPERPLASIA

23
Q

what drugs should be avoided in close angle glaucoma

A

Epi(a&B agonist) Atropine cause of mydriasis

24
Q

what are the liver flukes STEC

A

Schisto(mansoni Liver cancer, Hematobium Squamous bladder cancer)
TOXOCARA=from dog or cat diah & larva penetrate the owner skin
ECHINOCOCCUS=LIVER CYST
CLONORCHIS=INCREASE in ALP

25
what is the fever cycle in P. malariae
every 3rd day
26
what is the fever cycle in P. falci
every other day most fatal
27
which Malariae lives in the RBC
viva, ovale, so when RBC dies it dies w/it
28
How does Quinine, Mefloquine, Primaquine works
it oxidized RBC=Lyse it
29
what anti Malaria drug is given for travel
Mefloquine (strt 2wks b4 travel, 1pill a wk b4 lvng & 4 wks after u return)
30
what occurs in crossover study
every participant receives all the interventions but @ a diff time/sequence