bone tumors Flashcards Preview

STEP 1 > bone tumors > Flashcards

Flashcards in bone tumors Deck (37):
1

osteoma is a tumor of what

bone

2

osteomas most commonly occur

surface of facial bones

3

osteomas are associated with what syndrome

gardner syndrome (FAP)

4

osteoid osteomas are benign tumors of what

osteoblasts

5

what part of bone do osteoid osteomas occur

cortex of long bones (femur)

6

bone pain that resolves with aspirin

osteoid osteoma

7

osteoblastomas occur in what bones

vertebrae

8

bone pain that does not resolve with aspirin

osteoblastoma

9

bony mass

osteoid osteoma

10

bony mass > 2cm with a radiolucent core

osteoblastoma

11

most common benign of tumor of bone

osteochondroma

12

tumor of bone with an overlying cartilage cap

osteochondroma

13

lateral projection of growth plate (metaphysis)

osteochondroma

14

osteochondromas can rarely transform to what tumor

chondrosarcoma

15

where do osteosarcomas occur

metaphysis of long bones

16

incidence of osteosarcomas (age range and risk factors)

most prevalent = children (Rb gene)
elderly: pagets and radiation exposure

17

sunburst on xray

osteosacroma

18

codman triangle

osteosarcoma

19

pleomorphic cells that produce osteoid

osteosarcoma

20

osteosarcomas are malignant proliferation of what cells

osteoblasts

21

multinucleated giant cells and stromal cells

giant cell tumor

22

giant cell tumors occur in what part of the bone

epiphysis

23

soup bubble appearance

giant cell tumor

24

locations of giant cell tumors

distal femur / proximal tibia (knee)

25

ewing sarcoma cells are derived from what origin

neuroectoderm

26

what two tumors arise in diaphysis

ewing sarcoma
osteoid osteoma

27

what part of bone does ewing sarcoma occur in

diaphysis

28

small round blue cells

ewing sarcoma

29

what bone tumors occur in males

osteochondroma

30

what bone tumors occur boys

ewing sarcoma

31

onion skin periosteal reaction on xray

ewing sarcoma

32

what tranaslocation occurs in ewing sarcoma

11,22

33

what fusion protein does the 11,22 translocatio make

EWS-FL I

34

benign tumor arising in the medulla of the small hands and feet

chondroma

35

where do chondrosarcomas occur

medulla of pelvis or central skeleton

36

most metastatic tumors create what type of lsions

lytic punched out

37

prostatic tumors create what lesions

osteoblastic