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Flashcards in ovarian neoplasms Deck (54):
1

most common type of ovarian tumor

surface epithelial tumor

2

BRCA1 mutation carriers have an increased risk of what type of cancer

serous carcinoma of ovary and fallopian tube

3

tumor composed of bladder-like epithelium (uroepithelium)

Brenner

4

are brenner tumors malignant or benign usually?

benign

5

tumor composed of endometrial-like glands

endometrioid tumor

6

are endometrioid tumors usually benign or malignant?

malignant

7

what is important to check after a diagnosis of ovarian endometrioid tumor?

check for endometrial carcinoma in uterus

8

single cyst with simple, flat lining

cystadenoma

9

tumor arising in premenopausal woman, 30-40 years

cystadenoma

10

CA-125 is only useful to monitor what type of ovarian tumors

surface epithlial tumors

11

how is prognosis of surface epithelial tumors

poor- worst prognosis of female genital tract cancers

12

second most common type of ovarian tumor

germ cell tumor

13

what age group do germ cell tumors occur

reproductive age

14

what age group do malignant surface epithelial tumors occur

older - 60-70

15

most common germ cell tumor

cystic teratoma

16

cystic tumor composed of fetal tissue derived from two or three embryological layers

cystic teratoma

17

are cystic teratomas benign or malignant

benign, but can have malignant potential if there is immature embryonic material present or somatic malignancy

18

what is the most common immature tissue found in a cystic teratoma

neural tissue

19

what is the most common somatic malignancy associated with cystic teratoma

squamous cell carcinoma of skin

20

what is a struma ovarii

cystic teratoma composed of primarily thyroid tissue

21

hyperthyroidism plus a mass in adnexal region

struma ovarii

22

what is the most common malignant germ cell tumor

dysgerminoma

23

tumor composed of large cells with clear cytoplasm and central nuclei

dysgerminoma

24

what is the testicular counterpart of dysgerminoma

seminoma

25

what is the prognosis and treatment of dysgerminoma

good prognosis, treated with radiotherapy

26

what marker is increased with dysgerminoma

LDH

27

endodermal sinus tumor is what kind of tumor

yolk sac tumor (germ cell)

28

most common germ cell tumor in children

endodermal sinus tumor (yolk sac)

29

5 yo girl with ovarian mass

endodermal sinus tumor

30

serum AFP is increased with this type of tumor

endodermal sinus tumor

31

schiller duvall body

endodermal sinus tumor

32

biopsy reveals glomeruloid like structures

schiller duvall body, associated with endodermal sinus tumor

33

malignant tumor composed of cytotrophoblast and syncytiotrophoblasts

choriocarcinoma

34

small, hemorrhagic tumor

choriocarcinoma

35

what marker is raised in choriocarcinoma

beta-HCG

36

where is beta hcg secreted from

syncytiotrophoblast

37

high beta-hcg can lead to what

thecal cysts in ovary

38

what part of normal placenta is absent in choriocarcinoma

villi

39

how does choriocarcinoma respond to chemo

poorly - heamtogenous spread very early on

40

malignant tumor composed of large primitive cells

embryonal carcinoma

41

granulosa-theca cell tumors secrete what

estrogen

42

prognosis of embryonal carcinoma

aggressive and metastasizes early

43

is granulosa theca cell malignant or benign

malignant but rarely metastasizes

44

reinke crystals

sertoli-leydig tumor

45

sertoli leydig cells can secrete what

androgens

46

presents with estrogen excess

granulosa-theca

47

presents with androgen excess

sertoli-leydig

48

pleural effusions and ascites plus ovarian tumor

meigs syndrome - fibroma

49

benign tumor of fibroblasts

fibroma

50

treatment of meigs syndrome

resolves with removal of tumor

51

mucinous cystadenocarcinoma bilateral or unilateral

usually unilateral

52

krukenberg

metastatic mucinous tumor, bilateral

53

massive amounts of mucus in peritoneum

psuedomyxoma peritonei

54

pseudomyxoma peritonii is due to mucinous tumor located where

appendix that metastasizes to ovary