ovarian neoplasms

Question 1

most common type of ovarian tumor

Answer 1

surface epithelial tumor

Question 2

BRCA1 mutation carriers have an increased risk of what type of cancer

Answer 2

serous carcinoma of ovary and fallopian tube

Question 3

tumor composed of bladder-like epithelium (uroepithelium)

Answer 3

Brenner

Question 4

are brenner tumors malignant or benign usually?

Answer 4

benign

Question 5

tumor composed of endometrial-like glands

Answer 5

endometrioid tumor

Question 6

are endometrioid tumors usually benign or malignant?

Answer 6

malignant

Question 7

what is important to check after a diagnosis of ovarian endometrioid tumor?

Answer 7

check for endometrial carcinoma in uterus

Question 8

single cyst with simple, flat lining

Answer 8

cystadenoma

Question 9

tumor arising in premenopausal woman, 30-40 years

Answer 9

cystadenoma

Question 10

CA-125 is only useful to monitor what type of ovarian tumors

Answer 10

surface epithlial tumors

Question 11

how is prognosis of surface epithelial tumors

Answer 11

poor- worst prognosis of female genital tract cancers

Question 12

second most common type of ovarian tumor

Answer 12

germ cell tumor

Question 13

what age group do germ cell tumors occur

Answer 13

reproductive age

Question 14

what age group do malignant surface epithelial tumors occur

Answer 14

older - 60-70

Question 15

most common germ cell tumor

Answer 15

cystic teratoma

Question 16

cystic tumor composed of fetal tissue derived from two or three embryological layers

Answer 16

cystic teratoma

Question 17

are cystic teratomas benign or malignant

Answer 17

benign, but can have malignant potential if there is immature embryonic material present or somatic malignancy

Question 18

what is the most common immature tissue found in a cystic teratoma

Answer 18

neural tissue

Question 19

what is the most common somatic malignancy associated with cystic teratoma

Answer 19

squamous cell carcinoma of skin

Question 20

what is a struma ovarii

Answer 20

cystic teratoma composed of primarily thyroid tissue

Question 21

hyperthyroidism plus a mass in adnexal region

Answer 21

struma ovarii

Question 22

what is the most common malignant germ cell tumor

Answer 22

dysgerminoma

Question 23

tumor composed of large cells with clear cytoplasm and central nuclei

Answer 23

dysgerminoma

Question 24

what is the testicular counterpart of dysgerminoma

Answer 24

seminoma

Question 25

what is the prognosis and treatment of dysgerminoma

Answer 25

good prognosis, treated with radiotherapy

Question 26

what marker is increased with dysgerminoma

Answer 26

LDH

Question 27

endodermal sinus tumor is what kind of tumor

Answer 27

yolk sac tumor (germ cell)

Question 28

most common germ cell tumor in children

Answer 28

endodermal sinus tumor (yolk sac)

Question 29

5 yo girl with ovarian mass

Answer 29

endodermal sinus tumor

Question 30

serum AFP is increased with this type of tumor

Answer 30

endodermal sinus tumor

Question 31

schiller duvall body

Answer 31

endodermal sinus tumor

Question 32

biopsy reveals glomeruloid like structures

Answer 32

schiller duvall body, associated with endodermal sinus tumor

Question 33

malignant tumor composed of cytotrophoblast and syncytiotrophoblasts

Answer 33

choriocarcinoma

Question 34

small, hemorrhagic tumor

Answer 34

choriocarcinoma

Question 35

what marker is raised in choriocarcinoma

Answer 35

beta-HCG

Question 36

where is beta hcg secreted from

Answer 36

syncytiotrophoblast

Question 37

high beta-hcg can lead to what

Answer 37

thecal cysts in ovary

Question 38

what part of normal placenta is absent in choriocarcinoma

Answer 38

villi

Question 39

how does choriocarcinoma respond to chemo

Answer 39

poorly - heamtogenous spread very early on

Question 40

malignant tumor composed of large primitive cells

Answer 40

embryonal carcinoma

Question 41

granulosa-theca cell tumors secrete what

Answer 41

estrogen

Question 42

prognosis of embryonal carcinoma

Answer 42

aggressive and metastasizes early

Question 43

is granulosa theca cell malignant or benign

Answer 43

malignant but rarely metastasizes

Question 44

reinke crystals

Answer 44

sertoli-leydig tumor

Question 45

sertoli leydig cells can secrete what

Answer 45

androgens

Question 46

presents with estrogen excess

Answer 46

granulosa-theca

Question 47

presents with androgen excess

Answer 47

sertoli-leydig

Question 48

pleural effusions and ascites plus ovarian tumor

Answer 48

meigs syndrome - fibroma

Question 49

benign tumor of fibroblasts

Answer 49

fibroma

Question 50

treatment of meigs syndrome

Answer 50

resolves with removal of tumor

Question 51

mucinous cystadenocarcinoma bilateral or unilateral

Answer 51

usually unilateral

Question 52

krukenberg

Answer 52

metastatic mucinous tumor, bilateral

Question 53

massive amounts of mucus in peritoneum

Answer 53

psuedomyxoma peritonei

Question 54

pseudomyxoma peritonii is due to mucinous tumor located where

Answer 54

appendix that metastasizes to ovary