Bones 2 Flashcards

1
Q

What is inflammation of the bones?

A

Osteitis/osteomyelitis

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2
Q

Trauma may cause osteoperiositis with formation of exostosis

A

Aseptic inflammation

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3
Q

Where does infection of the bone tend to localize?

A

Piglets -> vertebral bodies

Metaphysics of long bones due to microanatomy of vessels

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4
Q

What is a common source of osteomyelitis in neonates?

A

Omphalophlebitis (inflammation of the umbilical vein)

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5
Q

What is actinomycosis? What lesions does it cause? How does the animal usually get it?

A

AKA lumpy jaw (Actinomyces bovis)
Gram positive branching filamentous bacteria

Localized, chronic, granulomatous abscess of mandible (bone) -> facial distortion, loss of teeth, and dyspnea

Introduced via penetrating wounds of the oral mucosa from wire or coarse hay sticks

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6
Q

In a cat you have chronic pyogranulomatous osteomyelitis. What bacteria do you suspect?

A
Nocardia spp
(N asteroids is most common in dogs and cats) 

Pleomorphic, gram positive
Facultative intracellular

Infection follows wounds

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7
Q

What is usually observed in patients with an intra-thoracic space occupying mass?

A

Hypertrophic pulmonary osteoarthropathy/ osteopathy

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8
Q

Animal with painful swelling of limbs caused by peristaltic bone proliferation in long bones

A

Hypertrophic pulmonary osteoarthropathy/osteopathy

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9
Q

Hypertrophic pulmonary osteoarthropathy can occasionally be observed in young dogs with _________________ of the unitary bladder, and in mares with _________________

A

Rhabdomyosarcomas; ovarian tumors

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10
Q

Lion jaw is AKA? Who is it seen most commonly in?

A

Canine craniomandibular osteopathy

West highland white terriers

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11
Q

What is canine craniomandibular osteopathy?

A

Proliferative disorder confined to the bones of the skull, especially the mandibles, occipital and temporal bones -> discomfort when chewing or inability to open the mouth

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12
Q

Are bone neoplasia’ usually primary or secondary tumors?

A

Primary (primarily in dog, lesser in cat)

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13
Q

In what species are bone tumors usually malignant and what species tend to have benign bone tumors ?

A

Dog- malignant

Horse, cattle, and other domestic species - benign

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14
Q

What are the primary bone neoplasms?

A
Osteoma
Ossifying fibroma 
Osteosarcoma 
Chondroma 
Chondrosarcoma 
Multilobular tumor of bone
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15
Q

What is the most common primary bone tumor of dogs and cats?

A

Osteosarcoma

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16
Q

What breeds and age of dogs are most susceptible to osteosarcoma

A

Large breed - St. Bernard, Great Dane, Irish Setter, Boxer, Doberman, Rottweiler, and Labrador Retrievers

Mean age 7.5

More in males

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17
Q

What tumors accounts for approx 10% of primary bone tumors?

A

Chondrosarcoma

-involves flat bones (rib, nasal tubinates, and pelvis ) more than long bones

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18
Q

What are the types of joints?

A

Fibrous
Cartilaginous -united by hyaline cartilage or fibrocatilage
Synovial -covered by hyaline and articular capsule surrounding fluid filled cavity

19
Q

Joint injuries most commonly occur in synovial (diarthodial) joints, what are the results?

A

Fibrillation (fraying)

Eburnation “joint mice”

20
Q

What can form due to chronic joint injury?

A

Osteophyte

21
Q

What is villous hypertrophy/hyperplasia

A

Manifestation of chronic joint injury

Villi of hyperplasia extend from the synovial membrane

22
Q

What is a pannus?

A

Fibrovascular (granulation) and histocytic tissue that develops within the synovial membrane at its junction with the periosteum and cartilage margins.

Can spread over the articular surface as a velvety membrane

23
Q

What generic term is used to describe a joint with severe chronic injury?

A

End-stage joint

24
Q

What the appearance of an end-stage joint?

A
Variable degrees of damage to articular cartilage
deformation
osteophyte
Pannus formation
capsular fibrosis
synovial villous hypertrophy
Occasional ankylosis
25
What is ankylosis?
Fixation of the joint
26
What is osteochondrosis (dyschondroplasia)?
Abnormal growth and maturation of the articular cartilage
27
What is the most common cause of lameness in domestic animals?
Osteochondrosis
28
What form of osteochondrosis is characterized by the separation of a piece of articular cartilage form the subchondral bone?
Osteochondrosis dissecans (OCD)
29
What is characterized by a lack of conformity between the femoral head and acetabulum?
Hip dysplasia Large breed dogs!
30
What is an early finding to hip dysplasia?
Joint laxity (instability)
31
What is a Hansen's type I intervertebral disk disease?
Nucleus pulposa is extruded from the annulus fribrosis
32
What is a Hansen's type II inververtebral disk disease?
Protrusion of the nucleus pulposa into the annulus fibrosis (still within capsule)
33
Osteophyte formation at ventral and lateral margins of vertebral bodies adjacent to vertebral spaces
Spondylosis AKA Spondylosis defomans Ankylosing spondylosis
34
What is primary degenerative joint disease?
No apparent predisposing cause. Generally observed in older animals
35
What is secondary degenerative joint disease?
Associated with underlying abnormality in the joint or its supporting structures which leads to premature degeneration of the articular cartilage (eg hip dysplasia/trauma/inflammation)
36
What is a degenerative diseases in horse affecting the inter-phalangeal joints??
Ring bone Common in horses used in rodeo or polo-> chronic trauma from abrupt stops/turns
37
What are common bacteria in septic arthritis of cattle?
Trueperella pyogenes E.coli (calf) Histophilus somni Mycoplasma bovis
38
What are common bacterial isolates from septic arthritis in swine?
``` Trueperella Erysipelothrix Strep suis Haemophilus suis and parasites Mycoplasma hyorrhinis Micocpalsma hyosynoviae ```
39
What is a common bacteria isolated from septic arthritis of dogs and humans
Borrellia burgdorferi
40
What is caprine arthritis-encephalitis (CAE)?
Retrovirus > respiratory and neurological syndrome -> joint lesions are characterized by a lymphocytic hyperplastic synovitis with formation of carpal hygromas
41
What is a hygroma?
Chronic lesions that appears as a flattened cystic fluid filled subcutaneous distention over the crainal carpus
42
Non-infectious arthritis etiology? What is the pathogenesis ??
Immune -mediated Persistence of antigen in the synovial membrane of affected joints -> deposition of the immune complexes derived from inflammatory lesions -> erosive and non-erosive forms described
43
Malignant neoplasms of joints arise from _____________
Synovial membrane
44
What are the two types of malignant neoplasms of joints?
Synovial cell sarcoma : malignant tumor arising form synovial fibrocyte origin Histocytic sarcoma: malignant tumor arising form cells of histocytic phenotype, possible dendritic (Langerhans) cells present in the synovium