Neoplasia

Question 1

A lesion that in an irreversible uncontrolled growth is called ____________

Answer 1

Neoplasia

Question 2

Tumor means ?

Answer 2

Swelling

Question 3

Cancer means?

Answer 3

Malignant

Question 4

What are the two types of neoplasms

Answer 4

Benign

Malignant

Question 5

What cells are present in neoplasms

Answer 5

Parenchymal

CT and blood vessesl

Question 6

Parenchymal cells can be?

Answer 6

Epithelial

Mesenchymal

Question 7

Are endothelial cells epithelial or mesenchymal?

Answer 7

Mesenchymal

Question 8

Mesenchymal cells are derived from the ________

Answer 8

Mesoderm

Question 9

Cells that are round to spindle shaped with scant cytoplasm

Answer 9

Mesenchymal

Question 10

CT, muscle, and bone marrow are epithelial or mesenchymal cells?

Answer 10

Mesenchymal

Question 11

Are mucosa and glands epithelial or mesenchymal

Answer 11

Epithelial

Question 12

Epithelial cells are derived from?

Answer 12

Endoderm
Ectoderm
Mesoderm

Question 13

Cells that are squamous/cuboidal/ columnar

Answer 13

Epithelial cells

Question 14

The suffix for a benign epithelial cell neoplasm

Answer 14

-oma

Question 15

The suffix for a benign mesenchymal cell neoplasm

Answer 15

-oma

Question 16

The suffix for a malignant epithelial cell neoplasm

Answer 16

-carcinoma

Question 17

The suffix for a malignant mesenchymal cell neoplasm

Answer 17

-sarcoma

Question 18

The MDx for a neoplasm should include?

Answer 18

Location(organ)
Tissue origin
Growth behavior (benign/malignant )

Question 19

Name it:

Deer with a benign growth on the dermis of the skin originating from fibrous CT

Answer 19

Derma fibroma

Question 20

Name it:

Dog with malignant growth in nasal cavity originating from fibrous CT

Answer 20

Nasal fibrosarcoma

Question 21

Name it

Dog with a benign growth in the dermis of the skin originating from vascular endothelium

Answer 21

Dermal hemangioma

Question 22

Name it

Dog with a malignant growth in the spleen originating fro the vascular endothelium

Answer 22

Splenic hemangiosarcoma

Question 23

Name it

Dog with a benign growth derived form the perianal gland

Answer 23

Perianal adenoma

Question 24

Name it

Dog with a malignant growth derived from perianal gland

Answer 24

Perianal adenocarcinoma

Question 25

Name it Horse with a benign growth on the mandible

Answer 25

Mandibular osteoma

Question 26

Name it Dog with malignant growth in the maxilla

Answer 26

Maxillary osteosarcoma

Question 27

Name it Dog with a benign growth in the oral mucosa originating from squamous epithelial cells

Answer 27

Oral/labial papilloma

Question 28

Name it Cat with malignant growth in the organ mucosa originating from squamous epithelial cells

Answer 28

Oral squamous cell carcinoma

Question 29

Name it Cow with malignant growth in the lymph node

Answer 29

Lymphoma or lymphosarcoma

Question 30

Name it Ovarian tumor derived from more than 1 cell lineage

Answer 30

Ovarian teratoma

Question 31

The extent to which tumor cells resemble normal parenchymal cells

Answer 31

Differentiation

Question 32

A well-differentiated tissue will resemble what?

Answer 32

The tissue of origin

Question 33

Is earlier or later arrest associated with malignancy

Answer 33

Earlier

Question 34

What are features of anaplasia that are observed in malignant neoplasms

Answer 34

Pleomorphic Anisokaryosis (variable nucleus size) Nuclear hyperchomasia (extra DNA) high N:C ratio Prominent nucleoli Multiple nuclei Abnormal mitotic figures

Question 35

What are the characteristics used to compare benign and malignant tumors

Answer 35

Differentiation Growth rate Local invasion Metastasis

Question 36

Benign or Malignant?? Usually lack of differentiation Structure atypical Variable degree of anaplasia

Answer 36

M

Question 37

Benign or Malignant ?? Slow, progressive evasion Rare mitotic figure Normal mitotic figure

Answer 37

B

Question 38

Benign or Malignant?? Slow/rapid growth Erratic growth rate Numberous/abnormal mitotic figures

Answer 38

M

Question 39

Benign or Malignant?? Cohesive and expansile growth Capsule often present

Answer 39

B

Question 40

Benign or Malignant? Infiltrative growth Usually no capsule

Answer 40

M

Question 41

Benign or Malignant?? Metastatic

Answer 41

M

Question 42

Benign or Malignant ?? Structure similar to tissue Slow, progressive expansive Cohesive and expansile growth

Answer 42

Benign

Question 43

What is the most solid criteria for determining benign/malignant?

Answer 43

Metastasis

Question 44

What is more fatal, benign or Malignant?

Answer 44

Trick question Can be both Eg benign in the brain => death

Question 45

Is a cell with an abnormal mitotic figure benign or Malignant?

Answer 45

M

Question 46

What is the mitotic index

Answer 46

Number of mitosis in 10 high power fields