Breast Cancer Flashcards Preview

THERAPEUTICS III TEST 4 > Breast Cancer > Flashcards

Flashcards in Breast Cancer Deck (13):
1

what is the most common type of invasive breast cancer

invasive or infiltrating ductal carcinoma (IDC)

2

what are some risk reduction options for breast cancer

mastectomy
oophorectomy
tamoxifen
raloxifene

3

what is the primary screening method for breast cancer

mammography

4

At what age breast self exam be done

starting at age 20

5

At what age and how often should clinical breast exams (CBE) be done

every 3 years for women in their 20s and 30s; yearly after age 40

6

At what age and how often should mammograms be done

annually beginning at age 40

7

what are the lymph nodes that cancer normally spreads to first in breast cancer

sentinel lymph nodes

8

what are the poor prognosis factors for breast cancer

less than 35 years old
tumor size
nodal involvement
Histological Grade III
estrogen receptor negative status
HER2 positive disease

9

what drug should be added for HER2 positive breast cancer patients

trastuzumab (Herceptin)

10

If a patient is premenopausal at diagnosis, what should be used for adjuvant endocrine therapy for breast cancer

tamoxifen for 5 years

11

If a patient is post menopausal at diagnosis, what is first line treatment for breast cancer

aromatase inhibitors for 5 years

12

what are the adverse effects of tamoxifen

1. thrombotic events
2. vasomotor symptoms: hot flashes and vag dryness
3. endometrial cancer

13

what are the adverse effects of aromatase inhibitors

vasomotor symptoms
athralgias and myalgias
osteoporosis