cancer 2 Flashcards Preview

THERAPEUTICS III TEST 4 > cancer 2 > Flashcards

Flashcards in cancer 2 Deck (13):
1

what is the length of the tumor cell cycle known as?

doubling time

2

what is the proportion of actively dividing tumor cells known as?

growth fraction

3

Typically how many tumor cells are needed for a diagnosis of cancer

10^9

4

what is the tumor burden

number of cancer cells, size of tumor and amount of cancer in the body

5

what is the cell-kill hypothesis

a certain percentage of cancer cells will be killed with each course of chemo (independent of number of tumor cells)

6

what is a schedule dependent chemotherapy agent

cell cycle phase specific chemotherapy

7

what types of cancers have screening guidelines

breast
colon
prostate
cervical

8

what are the 7 warning signs of cancer

1. Change in bowel or bladder habits
2. A sore throat that will not heal
3. Unusual bleeding or discharge
4. Thickening or lump in breast
5. Indigestion or difficulty swallowing
6. Obvious change in a wart or mole
7. Nagging cough or hoarseness

9

what is the TNM Staging system

Tumor, Node, Metasteses staging
(t1-t4), (n0-n3), (m0-m1)

10

What are the stages of cancer

stage I - localized tumor
Stage II and III - local and regional extension of disease
Stage IV - Presence of distant metasteses

11

what are the grades of the ECOG performance status and what does it mean

0 = fully active
1 = restricted in strenuous activity
2 = awake and does self care but no work
3 = capable of only limited self care, confined to bed or chair 50% of waking hours
4. completely disabled
5. dead

12

what are the grades of the ECOG performance status and what does it mean

0 = fully active
1 = restricted in strenuous activity
2 = awake and does self care but no work
3 = capable of only limited self care, confined to bed or chair 50% of waking hours
4. completely disabled
5. dead

13

what are the grades of the ECOG performance status and what does it mean

0 = fully active
1 = restricted in strenuous activity
2 = awake and does self care but no work
3 = capable of only limited self care, confined to bed or chair 50% of waking hours
4. completely disabled
5. dead