C. Diff Pharm

Question 1

Most virulent strain of C. Diff

Answer 1

NAP-1/027

Question 2

Risk factors for C. Diff

Answer 2

Antibiotic use (especially those combos of clindamycin, penicillin, cephalosporins, fluroquinolones), hospitalization, Increased age,

Question 3

Drug of choice in mild C Diff

Answer 3

Metronidazole

Question 4

AE of metronisdazole?

Answer 4

Causes neuropathy, not good for pregnancy (crosses placenta and into breast milk)

Question 5

Vancomycin is the drug of choice for what kind of C Diff

Answer 5

Severe or recurrent. May also be given to pregnant pts. Can be given rectally.

Question 6

Fidaxomycin

Answer 6

Really expensive but its awesome because it leaves the normal flora intact, minimal systemitization, Better than vanc