Chlorpromazine
centrally acting anticholinergic and anti dopaminergic
Treats hiccoughs
Chlor—anti chol
motion sickness
meclizine and cyclizine…..antihistamines
Droperidol
Blocks D2 in CTZ…….Used for post operative nausea vomitting
The other post-op tx is metoclopramide….prevents post op nausea vomitting and stimulates gastric emptying
Granisetron
Cancer vomitting…serotonin antagonist
Dolasetron
like granisetron…serotonin antagonist….longer half life
Dol-lasts a long time
Aprepitant
Used adjunct for chemo….crosses the BBB so it acts centrally
Metabolized by CYP3A4
Lorazepem
Given prior to chemo