Cardiovascular Physiology Flashcards

(55 cards)

0
Q

What is ANP (atrial natriuretic peptide) released in response to?

A

Increased atrial pressure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

How many liters of blood per minute is pumped in a 70kg man

A

5-6 liters

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is BNP (b-type natriuretic peptide) released in response to?

A

overstretched ventricles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Intercalated discs allow the heart to contract in synchrony as one unit, what is this called?

A

Syncytium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is happening with the ions in the initial repolarization in cardiac muscle contraction?

A

Inactivation of Na+ influx

K+ efflux

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is happening in the plateau phase of the cardiac muscle contraction? (ions)

A

Ca++ influx through L-type Ca++ channels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What determines the force of contraction of the myocardial cell?

A

The amount of intracellular calcium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

No action potential can be initiated regardless of the stimulus strength, what refractory period is this?

A

Absolute refractory period

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

An action potential can be elicited, however a greater stimulus is needed, what refractory period is this?

A

Relative refractory period

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Why is cardiac muscle incapable of sustained contraction (tetany) as in skeletal muscle?

A

Because of the relatively long refractory period

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the Frank-Sterling law?

A

Cardiac output is directly proportional to venous return

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

The 1st heart sound is due to what?

A

Closure of the tricuspid and mitral valves

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

The 2nd heart sound is due to what?

A

Closure of the pulmonary and aortic valves

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

3rd heart sound occurs when?

A

After the 2nd heart sound and is seen in congestive heart failure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

The 4th heart sound is heard when?

A

Before the 1st heart sound and is seen in hypertrophic ventricles

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Systole (contraction) occurs between which heart sounds?

A

1st and 2nd

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Diastole (relaxation) occurs between which heart sounds?

A

2nd and 1st

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

If there is a prolonged PR interval (>200 milliseconds)

A

1st degree AV block

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

If there is progressive prolongation of the PR interval with dropped beats

A

2nd degree AV block (Mobitz 1- Wenckebach phenomenon)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Isovolumic contraction occurs when?

A

Between the closure of the AV valves and the opening of the aortic valve

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Increase in pressure without change in volume is called what?

A

Isovolumic contraction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What is it called when only 70ml of the 120ml of blood is expelled from the ventricle?

A

Ejection fraction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

A decrease in the ventricular pressure without a change in the volume is called?

A

Isovolumic relaxation

23
Q

When does isovolumic relaxation occur?

A

Between the closing of the aortic valve and the opening of the AV valves

24
Sympathetic control of heart rate comes from which vertebral levels and which sympathetic ganglia?
T1-T5, middle and inferior cervical ganglia
25
What is it called when the sympathetic nervous system increases heart rate?
Positive chronotropism
26
How does the sympathetic nervous system increase the heart rate?
By increasing the rate of Phase 4
27
What is it called when there is an increase in conduction velocity?
Positive dromotropism
28
How does the sympathetic nervous system increase conduction velocity?
By decreasing the PR interval
29
What is it called when there is an increase in force of contraction in the heart?
Positive inotropism
30
How does the sympathetic nervous system increase force of contraction?
By increasing Ca++ influx in Phase 2
31
Which CN controls parasympathetic control to the heart?
Vagus through its cardiac branches
32
Cardiac Output x Peripheral Resistance = ?
Blood Pressure
33
Stroke Volume x Heat Rate = ?
Cardiac Ouput
34
Afferent high pressure sensors (baroreceptors) information in the carotid sinus are carried in which nerve?
Cranial nerve IX
35
Afferent high pressure sensors (baroreceptors) information in the aortic arch is carried in which nerve?
Cranial nerve X
36
CN IX and CN X carry afferent high pressure baroreceptor information to which area of the brain?
The Medulla
37
Where are the low pressure baroreceptors located?
SVC, IVC and the right atrium
38
What do low pressure baroreceptors monitor?
Volume
39
What is Poiseuille's Law?
Peripheral resistance is directly proportional to viscosity of blood and lenth of the vessel and inversely proportional to the radius of the vessel raised to the 4th power
40
The greatest resistance in the vascular system is offered where?
Arterioles
41
Blood flow through a tubular structure is governed by which law?
La Place's law
42
What is La Place's law?
The pressure within a blood vessel is related to the tension, size and shape of the vessel
43
What is blood flow inversely proportional to?
The diameter of the blood vessel
44
How much of the total blood volume is contained within the venous system?
60%
45
How much of the total blood volume is contained within the pulmonary system?
15%
46
How much of the total blood volume is contained within the capillaries?
5%
48
Where is blood flow the greatest?
Within the arteries and veins
49
Where is the least amount of blood flow?
The capillaries
51
How much of the total blood volume is contained within the arteries and arterioles?
20%
52
Pressure which tends to force fluids out into the interstitial space (+)
Intracapillary hydrostatic
53
Pressure which tends to pull fluids into the capillary (-)
Intracapillary oncotic pressure
54
Pressure which forces fluids into the capillary
Interstitial hydrostatic pressure
55
Pressure which pulls fluid out of the capillary
Interstitial oncotic pressure
56
Prolonged exercise leads to cardiac muscle hypertrophy which leads to?
Athletic Heart Syndrome