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3rd year > CCLE 2 FINALSSSS > Flashcards

CCLE 2 FINALSSSS Flashcards

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1
Q
  1. Which of the following best describes hypersensitivity?
    A. Immune tolerance
    B. Excessive immune response
    C. Normal immune reaction
    D. Lack of immune response
A

Answer: B

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2
Q
  1. Hypersensitivity is an inappropriate or exaggerated response to:
    A. Bacteria only
    B. Self-antigens only
    C. A foreign antigen
    D. External temperature
A

Answer: C

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3
Q
  1. Who classified hypersensitivity into four types?
    A. Jenner
    B. Coombs and Gell
    C. Pasteur
    D. Koch
A

Answer: B

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4
Q
  1. Which of the following is not one of the four types of hypersensitivity?
    A. Type I
    B. Type II
    C. Type V
    D. Type IV
A

Answer: C

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5
Q
  1. Type I hypersensitivity is also known as:
    A. Cytotoxic reaction
    B. Delayed type
    C. Immediate hypersensitivity
    D. Immune complex-mediated
A

Answer: C

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6
Q
  1. Which immunoglobulin is involved in Type I hypersensitivity?
    A. IgA
    B. IgM
    C. IgG
    D. IgE
A

Answer: D

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7
Q
  1. Mast cells and basophils are sensitized by which antibody?
    A. IgA
    B. IgE
    C. IgM
    D. IgD
A

Answer: B

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8
Q
  1. Which cells release histamine in Type I reactions?
    A. Neutrophils
    B. Eosinophils
    C. Mast cells
    D. Macrophages
A

Answer: C

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9
Q
  1. A classic example of Type I hypersensitivity is:
    A. Serum sickness
    B. Allergic rhinitis
    C. Contact dermatitis
    D. Tuberculosis
A

Answer: B

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10
Q
  1. Which type of hypersensitivity is cytotoxic?
    A. Type I
    B. Type II
    C. Type III
    D. Type IV
A

Answer: B

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11
Q
  1. In Type II hypersensitivity, the antibodies involved are:
    A. IgE only
    B. IgG and IgM
    C. IgA
    D. IgD
A

Answer: B

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12
Q
  1. Hemolytic disease of the newborn is an example of:
    A. Type III
    B. Type IV
    C. Type I
    D. Type II
A

Answer: D

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13
Q
  1. Which antigen-antibody complex causes tissue damage in Type III hypersensitivity?
    A. Cell surface antigen
    B. Free antigen-antibody complex
    C. Self-antigen
    D. None
A

Answer: B

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14
Q
  1. Serum sickness is classified under:
    A. Type I
    B. Type II
    C. Type III
    D. Type IV
A

Answer: C

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15
Q
  1. Arthus reaction is an example of:
    A. Type I
    B. Type II
    C. Type III
    D. Type IV
A

Answer: C

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16
Q
  1. Type IV hypersensitivity is:
    A. Immediate
    B. Antibody mediated
    C. T-cell mediated
    D. IgE mediated
A

Answer: C

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17
Q
  1. Delayed type hypersensitivity takes how many hours to develop?
    A. 1–2 hours
    B. 4–6 hours
    C. 24–48 hours
    D. 10 minutes
A

Answer: C

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18
Q
  1. Which type involves granuloma formation?
    A. Type I
    B. Type II
    C. Type III
    D. Type IV
A

Answer: D

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19
Q
  1. Contact dermatitis falls under which type?
    A. Type I
    B. Type IV
    C. Type II
    D. Type III
A

Answer: B

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20
Q
  1. Which cell type is predominantly responsible for Type IV reactions?
    A. B cells
    B. T helper cells
    C. Mast cells
    D. Basophils
A

Answer: B

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21
Q
  1. Which chemical mediator is stored in granules of mast cells?
    A. Serotonin
    B. Histamine
    C. Leukotrienes
    D. Prostaglandins
22
Q
  1. Anaphylaxis is a feature of which hypersensitivity type?
    A. Type I
    B. Type II
    C. Type III
    D. Type IV
23
Q
  1. Autoimmune hemolytic anemia is an example of:
    A. Type I
    B. Type II
    C. Type III
    D. Type IV
24
Q
  1. In Type III reactions, complexes are deposited in:
    A. Nerves
    B. Lungs
    C. Blood vessels
    D. Muscles
25
25. Allergic asthma is classified as: A. Type I B. Type II C. Type III D. Type IV
Answer: A
26
26. Which hypersensitivity is antibody-independent? A. Type I B. Type II C. Type III D. Type IV
Answer: D
27
27. Tuberculin test is an example of: A. Type I B. Type II C. Type III D. Type IV
Answer: D
28
28. The earliest known classification of hypersensitivity was in: A. 1921 B. 1936 C. 1953 D. 1965
Answer: B
29
29. Coombs and Gell classification was developed in: A. 1953 B. 1963 C. 1970 D. 1942
Answer: A
30
30. Type I reaction is also known as: A. Delayed B. Anaphylactic C. Complement-mediated D. Arthus reaction
Answer: B
31
31. The term “anaphylaxis” was coined by: A. Pasteur B. Richet and Portier C. Gell and Coombs D. Jenner
Answer: B
32
32. Anaphylaxis involves which organ systems? A. Respiratory and cardiovascular B. Skeletal C. Endocrine D. Nervous
Answer: A
33
33. Hay fever is an example of: A. Type II B. Type IV C. Type I D. Type III
Answer: C
34
34. Urticaria is another term for: A. Anemia B. Fever C. Hives D. Bruising
Answer: C
35
35. Autoantibodies against thyroid cells in Graves’ disease are an example of: A. Type II B. Type IV C. Type III D. Type I
Answer: A
36
36. Cytotoxic hypersensitivity targets: A. Host cells B. Allergens C. Foreign DNA D. Pathogens only
Answer: A
37
37. All of the following are examples of Type III hypersensitivity except: A. Arthus reaction B. Serum sickness C. Rheumatoid arthritis D. Contact dermatitis
Answer: D
38
38. What leads to tissue damage in Type IV hypersensitivity? A. Antibody binding B. Complement activation C. T cell-mediated cytotoxicity D. IgE reaction
Answer: C
39
39. All of the following hypersensitivity reactions are antibody mediated except: A. Type I B. Type II C. Type III D. Type IV
Answer: D
40
40. Which hypersensitivity can be tested with a skin patch test? A. Type I B. Type II C. Type III D. Type IV
Answer: D
41
41. Which cytokine is important in Type IV hypersensitivity? A. IL-1 B. TNF-α C. IFN-γ D. IL-10
Answer: C
42
42. Which of the following is an example of local anaphylaxis? A. Bronchial asthma B. Serum sickness C. Systemic lupus D. Tuberculosis
Answer: A
43
43. An Arthus reaction occurs after: A. Initial sensitization B. Subsequent injection of antigen C. First exposure D. Infection
Answer: B
44
44. Which immunoglobulin causes allergic symptoms in Type I? A. IgA B. IgM C. IgG D. IgE
Answer: D
45
45. In Type II, antibody binds to antigen on: A. Food particles B. Tissue cells C. Mast cells D. Environmental allergens
Answer: B
46
46. Desensitization therapy is used in: A. Type II B. Type III C. Type I D. Type IV
Answer: C
47
47. Contact with poison ivy causes: A. Type I B. Type II C. Type III D. Type IV
Answer: D
48
48. Farmer’s lung is a result of: A. Type I B. Type II C. Type III D. Type IV
Answer: C
49
49. Which type of hypersensitivity is involved in graft rejection? A. Type I B. Type II C. Type III D. Type IV
Answer: D
50

3rd year (35 decks)

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