Cells and Tissues Flashcards
(26 cards)
Organelles and specialisations expected in a secretory cell
Lots of:
- rER
- Golgi Apparatus
- Mitochondria
Organelles and specialisations expected in absorpative cell
Lots of:
- Mitochondria
- Microvilli
- Cell junctions
Responsibilities of cytoskeleton
Maintenance of cell’s shape and movement
Components of cytoskeleton
- Microfilaments
- Intermediate filaments
- Thick filaments
- Microtubules
Identify main component of Microfilament and its role
Actin; Forming contractile skeleton; regulating cell shape and tactile activity
Intermediate Filaments
Vibramentin or Cytokeratin - Keeping organelles in place and anchoring them to the cell membrane
**ALSO DESMIN AND LAMININ
Microtubules
Responsible for positioning of organelles and cell shape changes. Used in centrioles in cell division and cilia formation
Cilia
Extensions of the microtubule cytoskeleton that actively move
Microvilli and what they consist of
Extensions of the actin microfilament cytoskeleton, no active movement; role is to increase surface area
Structure of Cilia and how this causes movement
9 Pairs of microtubules surrounding a core pair. Each is attached to the next one and the core. They attach and detach at the same time to cause a beating
What are Centrioles made of
groupings of microtubules arranged in a 9 (triplets) + 0 pattern
Tight/Barrier/Occluding Junction
Prevent the passage of substances between cells and helps maintain position of membrane proteins
Adherens Junction/Zonula Adherens
Extension of actin cytoskeleton and attaches adjacent cells together to form a structural sheet
Desmosomes
Extension of intermediate fillament cytoskeleton and attaches adjacent cells together to form a structural sheet
(Like Zonula Adherens)
Difference between Desmosomes and Zonula Adherens
Adherens Junctions are made of actin/microfilaments while Desmosomes are made of intermediate filaments
**BOTH HAVE CADHERENS I THINK
Hemidesmosomes
Anchoring junctions attach epithelia to basement membrane and hence tissue beneath (e.g. skin)
What are Hemidesmosomes made of
Integrins
Laminin collagen
Gap junctions and what does it permit
For direct communication - Passage of ions, amino acids, sugars, second messangers, metabolites
Permits coordinated cell activity - e.g. heart/muscle
What are Gap Junctions made of
Connexins which assemble into connexons
Junctional Complex Orientation
Top to Bottom:
- Occluding
- Adherent
- Desmosomes
- Gap Junction
OADG
4 Basic tissue types
- Epithelium
- Connective Tissue
- Muscle
- Nerve
3 Germ Layers
- Ectoderm
- Mesoderm
- Endoderm
Epithelia
Sheets of closely packed cells derived of any of the 3 germ layers which cover a surface
Connective tissue and which germ layer is it derived from
Cells dervied from mesoderm and producing an extracellular matrix of fibres