Gametogenesis & Fertilisation Flashcards

(38 cards)

1
Q

Finger like projections of fallopian tubes

A

Fibmbriae

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2
Q

Regions of Fallopian Tube (From Ovary to Uterus Direction)

A

Infundibulum
Ampulla
Isthmus
Interstitial/Intermural Region

Im always irrationally irritated

Innit fun, die bully?

Arm puller

Is miss listening

Just remember the last one

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3
Q

Summary of Oogenesis

A

That is all

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4
Q

Region of fallopian tube where fertilisation tends to take place

A

Ampulla

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5
Q

Where are the eggs of the ovary released into

A

Abdominal/Peritoneal Cavity to be caught by fimbriae

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6
Q

How many primary follicles develop monthly after female puberty

A

5-12 primary follicles

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7
Q

Septum Pellucidum and what is it made of

A

Separation between ovum and the growing follicles around it

It is an acellular mucopolysaccharide layer/GAGs

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8
Q

When are oogonia formed

A

Before birth

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9
Q

What happens to oogonia after birth (don’t just say they become x)

A

A single layer of follicular cells surround the egg

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10
Q

What happens to all but one (mostly) of the growing follicles

A

Degeneration to form a small Corpus Atreticum or Scar

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11
Q

What happens to the remaining growing primary follicle(s) - that do not degenerate

A

A fluid filled space (Antrum) appears in the surrounding cells; those cells begin to secrete oestrogen

The outside cells are dubbed theca externa; inside are theca interna

Extrerna are mostly inactive & avascular while interna produce oestrogen

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12
Q

How is the secondary follicle referred to

A

Graafian Follicle

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13
Q

Stratum Granulosum (oogenesis)

A

Cells in graafian follicle that do not surround oocyte and instead surround the enlarged antrum
They produce progesterone

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14
Q

Cumulus Oophorus

A

Cells that surroud the oocyte in the graafian follicle

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15
Q

What is released from the mature follicle when it ruptures

A

Ovum

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16
Q

What do the cells that directly surrounded the oocyte (Cumulus Oophorus) in the graafian follicles become

A

Corona Radiata

17
Q

What happens to the septum pellucidum after ovum formation

A

Expansion to become the zona pellucida

18
Q

Diamater of ovum

A

130 Micrometers

19
Q

What happens to the Stratum Granulosum of oogenesis

A

It becomes the corpus luteum

20
Q

What happens to the corpus luteum if there is no fertilisation

A

It degenerates into the corpus albicans

21
Q

What is the lifespan of the corpus luteum

22
Q

What happens to the chromosomes of the diploid egg when dividing and also to the haploid egg during fertilisation

A

They form Polar Bodies

23
Q

What does the embryo do to the corpus luteum

A

Secretes hCG (Human Chorionic Gonadotropin) which sustains the corpus luteum for it to become the corpus luteum of pregnancy (which eventually degenerates into the corpus albicans anyway)

24
Q

Summarise Spermatogenesis

A

Stem Cells divide into spermatogonium (46 chromosomes)

Divide to form primary spermatocytes (46)

Undergo 1st meiosis to form secondary spermatocyes (23, X or Y)

2nd meiosis to form spermatids (23, X or Y)

Maturation to become spermatozoa (23, X or Y)

Stem Cells, SpermatoGonia, Primary, Secondary, Spermatids, Spermatozoa

Sam Got Pissed, So Tomorrow; Zoo!

25
What covers the nucleus in the head of a spermatozoon and what is it covered by
Acrosomal Cap and it is covered by a glycoprotein surface
26
What is the structure of the sperm flagellum like
Axial bundle with cilia 9+2 microtubule arrangements
27
What is contained in the middle piece of a spermatozoon and why
Spiral arrangement of mitochondria to provide energy for movement of sperm
28
Capacitation
Conditioning of sperm in female reproductive tract during which acrosomal region loses glycoprotein coat
29
Compare Cytoplasmic:Nuclear Ratio of Eggs vs Sperm
Eggs: High Sperm: Low
30
What percentage of sperm penetrate the cervix
1%
31
What happens once sperm reach isthmus and how is this reversed
Become less motile Chemoattractants released from cumulus cells on ovulation make sperm motile again to swim to ampulla
32
Why are there sometimes 3 polar bodies in a fertilised egg
The first polar body divides
33
At which part of meiosis is the ovum suspended at before fertilisation
Metaphase II
34
What mechanisms prevent polyspermy
Zona Reaction (a.k.a Cortical) Hardeneing of zona pellucida Enzymes released by cortical granules digest sperm receptor proteins ZP2 & ZP3 so they can no longer bind sperm
35
State of Embryo 30h Post Fertilisation
Formation of 2 Daughter blastomeres (cells) formed by mitosis after fertilisation
36
Further Cleavage
More cells made which get smaller since no further cytoplasm is made and outer membrane is defined DNA synthesis but Virtually no protein
37
Morula
Solid ball of cells after fertilisation Normal ish cyto:nuc ratio Zona pellucida persists to prevent polyspermy fun fact: latin for mulberry because people thought thats what it looks like Free within uterine cavity
38
Blastocyst vs Morula
Outer layer of cells form tight/occluding junctions in blastocyst - compaction Zona pellucida breaks down - cracks appear