Flashcards in Chapter 23 - Antiseizure Agents Deck (18):
Control of tonic-clonic and psycho motor seizures, prevention of seizures during neurosurgery, Control of status epilepticus.
Stabilizes neuronal membranes and prevents hyperexcitability caused by excessive stimulation; limits the spread of seizure activity from an active focus; has cardiac antiarrhythmic effects similar to those of lidocaine.
stevens johnson syndrome
CI: Discontinuing may lead to status epilepticus
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hepatic impairment *
Long term treatment of tonic-clonic and cortical focused seizures, emergency control of certain acute convulsive episodes and anticonvulsant treatment of generalized tonic clonic seizures and focal seizures (parenteral).
General CNS depressant inhibits impulse conduction in the ascending RAS depresses the cerebral cortex alters cerebellar function depresses motor output and can produce excitation, sedation, hypnosis, Anesthesia, and deep coma.
tissue necrosis at site
CI: same as hydantoins
management of anxiety disorders acute alcohol withdrawal; Muscle relaxing, Treatment of tetanus, Adj. in status epilepticus and severe recurrent convulsive seizures, Preoperative relief of anxiety and tension, management of epilepsy and patients require intermittent use to control increased seizure activity
Acts in the limbic system and reticular formation, potentiates the effects of GABA, has little effect on cortical function.
Paradoxical excitatory reactions
I: Control of absence seizures
A: may act in inhibitory neuronal systems suppresses the electroencephalographic pattern associated with absence seizures, reduces frequency of attacks.
Stevens Johnson syndrome
CI: Intermittent porphyria
Partial Seizure Drugs
Treatment of seizure disorders including partial seizures with complex patterns; tonic clonic seizures; Mixed seizures; trigeminal neuralgia.
Inhibits polysynaptic responses and blocks posttetanic potentiations; mechanism of action is not understood; related to tricyclic antidepressants.