Chapter 8 Flashcards

(51 cards)

0
Q

Nitrogenous base
Deoxyribose
Phosphate group

A

Nucleotide

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1
Q

Macromolecule composed of repeating unite called nucleotides

A

DNA

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2
Q

Pentose sugar ribose with one less oxygen in DNA or ribose in RNS

A

Deoxyribose

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3
Q

The molecular study of genomes

A

Genomics

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4
Q

Set of rules that determine how nucleotide sequence is converted into amino acid sequence of proteins

A

Genetic code

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5
Q

Gene usually codes for mRNA which ultimately results in the formation of proteins
Proteins can also be a rRNA or a transfer RNA

A

Genetic Code

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6
Q

The entire DNA or collection of genes. It is the entire genetic material of an organism. It represents the POTENTIAL properties

A

Genotype

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7
Q

It refers to the actual EXPRESSED properties of an organism. It is an organisms collection of proteins

A

Phenotype

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8
Q

Process of DNA replication as each double stranded DNA molecule has one original mother strand and one new synthesized strand

A

Semiconservative

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9
Q

DNA polymerase enzyme can add new nucleotides at the 3’ end of the newly synthesized strand only, so the DNA is synthesized in one direction

A

5’-3’

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10
Q

Lagging strand synthesis is discontinuous as it’s made in fragments

A

Okazaki fragments

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11
Q

Enzyme opens the double helix up, so a replication fork

A

Helicase

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12
Q

Makes a short piece of RNA called RNA primer on the DNA TEMPLATE

A

RNA polymerase

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13
Q

Adds nucleotides at the 3’ end of the RNA primer and make the daughter strand. It also does the proof reading mistakes in base pairing

A

DNA Polymerase I

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14
Q

Removes RNA Primer and replaces it with DNA nucleotides but cannot connect the two newly made segments together

A

DNA polymerase I

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15
Q

Joins the newly made fragments

A

DNA Ligase

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16
Q

Relaxes supercoiled ahead of replication fork

A

DNA GYRASE

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17
Q

Protein synthesis, it involves decoding the language of nucleic acids and converting information into protein language

A

Translation

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18
Q

AUG

A

Initiator codon

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19
Q

UAA
UGA
UAG

A

Terminator codons

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20
Q

Combines with certain proteins to make ribosomes

21
Q

site for protein synthesis
Copy DNA info for synthesis of proteins
Have codons in triplet bases

22
Q

Pick up specific amino acids in cytoplasm and transfer them to mRNA

Cloverleaf shape with attachment site for a specific amino acid
Has anti-codon complementary to codon in mRNA

23
Q

Codes for particular amino acid

24
Coding regions of DNA
Exons
25
Non coding regions
Introns
26
Regulatory proteins that block the binding of RNA polymerase to DNA No transcription
Repressor protein
27
Process that turns on the transcription of a gene
Inducer
28
B-galactosides production in E.coli Converts lactose to glucose and galactose When lactose present it is converted to allolactose that induces the gene to produce the enzyme B-galactose
Induction
29
Area on gene where RNA polymerase binds.
Promotor
30
Area where Repressor can bind
Operator
31
Set of promotor and operator sites and the structured gene thru control are defined as operon
Operon
32
Maybe silent or neutral | Nucleotide is substituted for other especially in third position of codon
Mutations
33
Missense mutations | Nonsense mutations
Point mutation
34
Which single base is replaced by another base
Point mutation
35
Base substitution resulting in an amino acid substitution. Suckle cell causes by this mutation
Missense mutation
36
Base substitutions resulting in a nonsense codon (stop codon) in the middle of mRNA (half product or no product)
Nonsense mutation
37
Positive selection involves detection of mutant cells by rejection of unwanted parent cells
Direct mutation
38
Negative selection selects cells that cannot preform a certain function by using replica plating
Indirect mutants
39
Genes are transferred from a donor to a recipient Donor does not give entire chromosome Gene transfer can occur between species
Unidirectional
40
Genes are passed from an organism to its offspring
Vertical gene transfer
41
Bacteria pass their gene to other microbes of the same generation Transformation Conjugation Transduction
Gene transfer
42
Genes are transferred from one to another bacterium as naked DNA Some bacteria release their DNA into environment. Other bacteria encounter that DNA
Transformation
43
Bacteria take up fragments of DNA and integrate then into their own chromosome by recombination Fredrick Griffith in 1926 Strep pneumoniae
Transformation
44
Bacteria that can pick up fragments of DNA from environment Me works best when donor and recipient cells are closely rebated Occurs in Bacillus, Haemophillus, neisseria, Acinetobacter, streptococcus, staph E. Coli
Transformation
45
Gene transfer from donor to a revue over by direct physical contact between cells which is mediates by plasmids
Conjugation
46
Has F factor | Sex pilus
Donor
47
Lacks F factor
Recipient
48
Give transfer from a donor to a recipient by was of a bacteriophage
Transduction
49
In which only certain donor genes can be transferred
Specialized transduction
50
Self replicating circular extra chromosomal molecules of DNA carrying genes that are not usually essential for the cells survival
Plasmids