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Flashcards in ckd3 Deck (12):
1

what should be started first: erythropoiesis-stimulating agents or iron

iron

2

at what level should ESA be considered

hgb = 9-10

3

at what level shold ESA be stopped

hgb exceeds 10
(or 11 on dialysis

4

what is the dosing form, strength, and interval for epoetin alfa?
how bout in dialysis pts

50-100 units/ kg subq once weekly or every 2 weeks

dialysis: same, but IV and 1-2 times weekly

5

what is the dosing form, strength, and interval for darboepoetin?
how bout in dialysis

.45 mcg/kg subq monthly

dialysis: .45 mcg/kg IV weekly or .75 mcg/kg IV every two weeks

6

what is goal Hgb

11-12

7

how often should Hgb be checked during ESA therapy

every 2 weeks until stable, then monthly

8

doses of ESA should be changed in what time frame and increments?

once monthly by 25% max

9

what level of Hgb change in two weeks calls for an increased dose

less than 1 g/dl change in hgb

10

what level of Hgb change in two weeks calls for a decreased dose

more than 2 g/dl change in hgb

11

what is BBW with ESAs

increased risk of CV events and mortality when target Hgb is > 11

12

what is the most common adverse effect of ESAs

hypertension