Flashcards in Clinical aspects of lipids Deck (16)
Situations when you should measure lipids?
-MI, CVA, other vascular disease
Main treatment options for lipids?
Others= PCSK9 inhibitors, ezetimibe, fibrates
Describe a lipid?
-All lipids are fats
-Low solubility in water
-Biochemically very diverse
How are you likely to come across lipids?
Fatty deposits in tendons - xanthomata
Xanthelasma- fatty deposits around eyes
What we measure in practice?
Triglycerides as requested
Calculate total HDL cholesterol ratio
LDL cholesterol calculated as requested
What should balance of HDL and LDL be?
More LDL than HDL
Lipid hypothesis essentially?
That having too much lipid in your blood is a risk factor for CVD?
Why are statins important?
They lower cholesterol but they also inhibit the atherosclerotic mechanism and can sometimes reduce the atherosclerosis in arteries
Statins that you will come across?
Examples of PCSK9 inhibitors?
Classes of lipid medications
Lots of evidence that it reduces mortality
Efficacy isn't the best
Isn't really prescribed
One of the most commonly prescribed