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Flashcards in cytogenics flash Deck (10)
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1

Questions

answers

2

Mitosis

Converts 2N-->4N-->2N (but with 2 cells). Nondisjunction called mosaicism.

3

Meiosis

Generate haploid from diploid. Independent assortment. Crossing over.

4

Crossing over

Meiosis prophase 1: Homologous chromosomes (chromatids) line up and crossover in area known as chiasma. Basis of genetic linkage.

5

Acrocentric

Stalk

6

Isochromosome

Abnormal centromere division. Iso-p or iso-q. Loss of genetic material.

7

Robertsonian translocation

Translocation between acrocentric chromosomes, short acrostalk/ p is lost and the q's fuse. 45 chromosomes, problem with gamete formation (33% normal)

8

amniocentesis

0.5% risk, 15-16 weeks gestation, amniotic fluid obtained for cytogenetic study by placing needle in uterus

9

chorionic villus sampling

0.5% risk, 10-12 weeks, remove cells from placenta (chorion) for cytogenetic study, remove mothers cells

10

Cordocentesis

1-2% risk, 18 weeks, umbilical blood sampling