Derived Lipids 2 Flashcards

1
Q

Derived lipids include hydrolysis of simple and complex lipids such as:

A
  • fatty acids
  • glycerol
  • steroids
  • other alcohols
  • fatty aldehydes
  • ketone bodies
  • hydrocarbons
  • lipid-soluble vitamins and micro-nutrients
  • hormones
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2
Q

Fatty acids are derived lipids, since fatty acids are

A

hydrolytic products of simple and compound lipids

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3
Q

Structure of fatty acids

A

chemically organic acids with aliphatic hydrocarbon chain of varying length (C2-C26) with mono terminal carboxylic acid group as functional group

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4
Q

Cholesterol is best known for its

A

aswsociation with atherosclerosis and heart disease

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5
Q

Steroids are the precursor of many equally important steroids including:

A
  • bile acids
  • adrenocortical hormones
  • sex hormones
  • vitamin D
  • cardiac glycosides
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6
Q

All steroids have a similar cyclic nucleus resembling

A

phenanthrene (rings A, B, and C) to which a cyclopentane ring (D) is attached

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7
Q

Steroids include:

A

chloesterol
estradiol
testosterone

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7
Q

Steroids include:

A

chloesterol
estradiol
testosterone

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8
Q

Cholesterol is an important part of

A

cell membranes, has a rigid ring system and a short branched hydrocarbon tail

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9
Q

Cholesterol serves as a component of

A

membranes of cells (increases or moderates membrane fluidity)

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10
Q

Cholesterol is a precursor

A

to steroid hormones and bile acids

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11
Q

Cholesterol function

A

storage and transport -cholesterol esters

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12
Q

Cholesterol is largely _________ but it has one polar group, a _____, making it ___________.

A

hydrophobic
hydroxyl
amphipathic

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13
Q

Cholesterol structure

A
  • 27 carbon atoms

- at C3 there is a -OH group: so it is an alcohol

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14
Q

Cholesterol is composed of

A

the steroid nucleus with methyl groups, an alkyl chain, and a hydroxyl group attached

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15
Q

When is cholesterol considered elevated?

A

If plasma cholesterol exceeds 200-220 mg/dL

16
Q

Cholesterol is

A

synthesized in the liver and obtained from foods

17
Q

Bile salts are synthesized from

A

cholesterol and stored in the gall bladder

18
Q

Bile salts emulsify (combined)

A

fats and oils to give a greater surface area for lipid digesting enzymes

19
Q

Steroid hormones are produced from

A

cholesterol

20
Q

Steroid hormones include sex hormones such as

A

androgens (testosterone) in males and estrogens (estradiol) in females