Phospholipids & Glycolipids Flashcards

1
Q

Phospholipids are amphipathic.

A

Lipids are insoluble in water since they contain a predominance of nonpolar (hydrocarbon) groups.

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2
Q

Some lipids contain ………….

Therefore, a part of the molecule is ……….. ‘water insoluble’ and a part is ………..’water soluble’

A

polar groups
hydrophobic
hydrophilic

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3
Q

Glycerophospholipds are also called

A

phosphoglycerides

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4
Q

Glycerophospholipids are

A

membrane lipids in which 2 fatty acids are attached in ester linkage to the 1st and 2nd carbons of glycerol, and a highly polar or charged group is attached through a phosphodiester linkage to the 3rd carbon

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5
Q

A glycerophospholipid has

A

polar and nonpolar regions

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6
Q

Phosphoglycerides are a major constituent of

A

cell membranes

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7
Q

Glycerophospholipds are named as

A

derivatives of the parent compound, phosphatic acid, according to the polar alcohol in the head group

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8
Q

A polar group is usually esterified to

A

Pi (usually serine, choline, ethanolamine, glycerol, or inositol)

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9
Q

In phosphoglycerides,

A

structure=function

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10
Q
In phosphoglycerides :
polar region-
nonpolar region-
........... character
ideal for forming ...........
A

glycerol, phosphate group, X
fatty acid
amphiphatic
bilayers

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11
Q

Glycolipids are important in

A

nerve tissues and in the cell membrane

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12
Q

Glycolipids are lipids with an attached

A

carbs or carb chains

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13
Q

Glycolipids are widely distributed in every

A

tissue of the body, particularly in nervous tissue such as brain

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14
Q

Glycolipids occur in the

A

outer leaflet of the plasma membrane , whre they contribute to cell surface carbs

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15
Q

The major glycolipids found in

A

animal tissues are glycosphingolipids

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16
Q

The major glycolipids found in

A

animal tissues are glycosphingolipids

17
Q

The major glycolipids found in

A

animal tissues are glycosphingolipids

18
Q

Sphingolipids are a large class of membrane lipids which have a

A

polar head group and 2 nonpolar tails

19
Q

How are sphingolipids different from glycerophospholipids?

A

they contain no glycerol

20
Q

Sphingolipids are composed of 1 molecules of the

A

long chain amino alcohol sphingosine
one molecule of a long-chain fatty acid
a polar head group that is joined by a glycosidic linkage in somecases and a phosphodiester in others

21
Q

Carbonds ___, ___, and __ of the sphingosine molecule are structurally ______ to the 3 carbons of ______ in glycerophospholipis

A

C-1 C-2 C-3
analogous
glycerol

22
Q

When a fatty acid is attached in amide linkage to the –NH2 on

A

C-2, the resulting compound is a ceramide

23
Q

What are the structural parents of all sphingolipids?

A

ceramides

24
Q

What are the 3 subclasses of sphingolipids?

A

sphingomyelins
neutral (uncharged) glycolipids
gangliosides

25
Q

Sphingomyelins contain

A

phosphochoine or phosphoethanolamine as their polar head group

26
Q

In sphingomyelins are classified along with

A

glycerophospholipids as phospholipids

27
Q

Sphingomyelins are present in the plasma membranes of animal cells and are especially prominent in

A

myelin, a membranous sheath that surrounds and insulates the axons of some neurons

27
Q

Sphingomyelins are present in the plasma membranes of animal cells and are especially prominent in

A

myelin, a membranous sheath that surrounds and insulates the axons of some neurons

28
Q

Cerebroside

A

a sphingolipid (ceramide) with a monosaccharide such as glucose or galactose as polar head group

29
Q

Ganglioside

A

a ceramide with polar head group that is a complex oligosaccharide, including the acidic sugar derivative sialic acid

30
Q

Both are cerebroside and gangliosides are known as

A

glycosphingolipids and are commonly found on the outer leaflet of the cell membrane

31
Q

Sphingolipids are

A

derivatives of sphingosine

32
Q

Sphingolipids at cell surfaces area sites of

A

biological recognition

33
Q

Glycosphingolipids as determinants of

A

blood groups