Discussion Post Qs

Question 1

the variable regions of receptors and antibodies are capable of high diversity because of ___ ___

Answer 1

gene recombination

Question 2

the ___ ___ of receptors and antibodies are capable of high diversity because of gene recombination

Answer 2

variable regions

Question 3

Can MHC cells interact with both MHC 1 and 2?

Answer 3

yes

Question 4

if the 2 process signal is disturbed, it becomes ___

Answer 4

anergic

Question 5

anergy is dependent on __-___

Answer 5

co-stimulation

Question 6

Which Ig has the longest half life

Answer 6

IgG

Question 7

Which Ig is the first to arrive on scene

Answer 7

IgM

Question 8

T/F: Can T helper cells shift subsets

Answer 8

False

Question 9

The type 2 pathogen response is initiated by?

A. Viruses

B. Bacteria

C. CD8+ cell binds to MHC 1 receptor to induce apoptosis

D. Worms

Answer 9

Worms

Question 10

T/F - Early in differentiation, Th cells may be able to shift between subsets.

Answer 10

True

Question 11

Which of the following cytotoxic cells are involved in organ transplant rejection

a. NK cells b. NKT lymphocytes c. CD8+ cytotoxic T lymphocytes d. A and C e. All of the above

Answer 11

D

Question 12

Which of the following cytotoxic cells is an innate lymphoid cell that lacks specific antigen receptors?

a. NKT lymphocytes b. NK cells c. CD8+ cytotoxic T lymphocytes d. A and B e. All of the above

Answer 12

B

Question 13

Which of the folling Th subsets is involved in sepressing immune response?

a. Th1 cells b. Peripheral Treg cells c. Th2 cells d. Tfh cells

Answer 13

B

Question 14

Which of the following Th subsets regulates affinity maturation of germinal center B cells

a. Tfh cells b. Th1 cells c, Th2 cells d. Peripheral Treg cells

Answer 14

A

Question 15

Where does FcRs bind to

Answer 15

Fc regions of antibodies

Question 16

The 3 high-affinity FcERI cells are?

Answer 16

Mast cells, esoinophils, and basophils

Question 17

The 2 low-affinity FcER cells are?

Answer 17

B cells and eosinophils

Question 18

PolygR stands for

Answer 18

Polymeric Immunoglobulin

Question 19

FcRn stands for

Answer 19

neonatal Fc receptor

Question 20

Which antibody mediated effector responses from the immunoglobulins depend on FcR? OAD

Answer 20

Opposition, ADCC, degranulation

Question 21

Which FcR is the main mediator of antibody functions?

Answer 21

FcR-gamma

Question 22

Which FcR initiates transcytosis of IgA and IgM from blood to lumen of GI, respiratory, or reproductive tract?

Answer 22

Fc PolyIgR

Question 23

What immunoglobulin does FcR-gamma bind?

Answer 23

IgG

Question 24

1. __ First antibody produced upon infection

Answer 24

IgM

Question 25

2. __ Protects mucous membranes

Answer 25

IgA

Question 26

3. __ Protects against all types of infections and is most abundant.

Answer 26

IgG

Question 27

4. __ Defends against allergens and is found on the surface of basophils and mast cells.

Answer 27

IgE

Question 28

5. __ Found on the surface of B cells.

Answer 28

IgD

Question 29

Which type of outcome (6 types) from antibody binding to antigen causes the antibody to bind to multiple antigens, and cross-links them for phagocytosis in large groups?

Answer 29

Aggulation